2-nitro-3-phenyl-2,3-dihydro-1H-benzochromene

Base Information

• Chemical Name: 2-nitro-3-phenyl-2,3-dihydro-1H-benzochromene
• CAS No.: 106824-26-4
• Molecular Formula: C₁₉H₁₅NO₃
• Molecular Weight: 305.333
• Mol file: 106824-26-4.mol

Synonyms:

Chemical Property of 2-nitro-3-phenyl-2,3-dihydro-1H-benzochromene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-nitro-3-phenyl-2,3-dihydro-1H-benzochromene

There total 6 articles about 2-nitro-3-phenyl-2,3-dihydro-1H-benzochromene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-nitro-3-phenyl-3H-naphtho<2,1-b>pyran (106824-27-5) → 3-(4-chlorophenyl)-2-nitro-2,3-dihydro-1H-benzo[f]chromene (106824-26-4,106824-28-6)

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; methanol; for 0.333333h; Ambient temperature;

DOI:10.1002/jhet.5570240343

Reference yield: 85.0%

2-nitro-3-phenyl-3H-naphtho<2,1-b>pyran (106824-27-5) → 2-nitro-3-phenyl-2,3-dihydro-1H-benzochromene (106824-26-4,106824-28-6)

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; methanol; for 0.333333h; Ambient temperature;

Reference yield: 73.0%

β-(2-hydroxy-1-naphthyl)nitroethane (96853-41-7) + benzaldehyde (100-52-7) → 3-(4-chlorophenyl)-2-nitro-2,3-dihydro-1H-benzo[f]chromene (106824-26-4,106824-28-6)

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; potassium fluoride; N,N-dimethylammonium chloride; In toluene; at 110 ℃; for 12h; diastereoselective reaction;

DOI:10.1002/ejoc.201600314

upstream raw materials:

2-nitro-3-phenyl-3H-naphtho<2,1-b>pyran

β-(2-hydroxy-1-naphthyl)nitroethane

benzaldehyde

acetic acid-(β-nitro-cinnamyl ester)

Refernces

• 1、 Huang, Chia-Yu,Kuo, Chun-Wei,Kavala, Veerababurao,Yao, Ching-Fa. "Syntheses of 2-Benzylbenzofuran Derivatives and 2-Aryl-nitrochroman Derivatives from Nitroalkene Precursors". . p. 2720 - 2734. Retrieved 2016/06/08.
• 2、 Varma, Rajender S.,Kadkhodayan, Miryam,Kabalka, George W.. "THE SYNTHESIS OF 2-PHENYL-3-NITRO-3,4-DIHYDRO-2H-1-BENZOPYRANS". . p. 1647 - 1652. Retrieved 2007/10/02.