Technology Process of 3(S)-<(tert-butyldiphenylsilyl)oxy>-4(E),6(Z)-dodecadienal
There total 6 articles about 3(S)-<(tert-butyldiphenylsilyl)oxy>-4(E),6(Z)-dodecadienal which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 79 percent / benzene / 6.5 h / 70 °C
2: 1.) n-BuLi / 1.) THF, from -78 deg C to RT, 30 min, 2.) THF, -78 deg C, 15 min
3: 1.) silver nitrate, N-chlorosuccinimide, 2.) DMSO / 1.) MeCN, H2O, -10 deg C, 10 min, 2.) MeCN, H2O, -10 deg C, 10 min
With
N-chloro-succinimide; n-butyllithium; silver nitrate; dimethyl sulfoxide;
In
benzene;
DOI:10.1021/jo00375a009
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 76.8 percent / sodium periodate / tetrahydrofuran; H2O; acetone / 0.25 h / Ambient temperature
2: 79 percent / benzene / 6.5 h / 70 °C
3: 1.) n-BuLi / 1.) THF, from -78 deg C to RT, 30 min, 2.) THF, -78 deg C, 15 min
4: 1.) silver nitrate, N-chlorosuccinimide, 2.) DMSO / 1.) MeCN, H2O, -10 deg C, 10 min, 2.) MeCN, H2O, -10 deg C, 10 min
With
sodium periodate; N-chloro-succinimide; n-butyllithium; silver nitrate; dimethyl sulfoxide;
In
tetrahydrofuran; water; acetone; benzene;
DOI:10.1021/jo00375a009
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 86 percent / trifluoroacetic acid / tetrahydrofuran; H2O / 6 h / Ambient temperature
2: 76.8 percent / sodium periodate / tetrahydrofuran; H2O; acetone / 0.25 h / Ambient temperature
3: 79 percent / benzene / 6.5 h / 70 °C
4: 1.) n-BuLi / 1.) THF, from -78 deg C to RT, 30 min, 2.) THF, -78 deg C, 15 min
5: 1.) silver nitrate, N-chlorosuccinimide, 2.) DMSO / 1.) MeCN, H2O, -10 deg C, 10 min, 2.) MeCN, H2O, -10 deg C, 10 min
With
sodium periodate; N-chloro-succinimide; n-butyllithium; silver nitrate; dimethyl sulfoxide; trifluoroacetic acid;
In
tetrahydrofuran; water; acetone; benzene;
DOI:10.1021/jo00375a009
