Technology Process of Z-Ser-Gln-OtBu
There total 1 articles about Z-Ser-Gln-OtBu which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
benzotriazol-1-ol; dicyclohexyl-carbodiimide;
In
N,N-dimethyl-formamide;
1.) 30 min, -20 deg C; 2.) 0 deg C, 2 h; 3.) r.t., 18 h;
DOI:10.1002/recl.19831021101
- Guidance literature:
-
Multi-step reaction with 2 steps
1: H2 / Pd/C / dimethylformamide
2: 100 percent / HOBt, DCC / dimethylformamide / 1.) 30 min, -20 deg C; 2.) 0 deg C, 2 h; 3.) r.t., 18 h
With
hydrogen; benzotriazol-1-ol; dicyclohexyl-carbodiimide;
palladium on activated charcoal;
In
N,N-dimethyl-formamide;
DOI:10.1002/recl.19831021101
- Guidance literature:
-
Multi-step reaction with 3 steps
1: H2 / Pd/C / dimethylformamide
2: 100 percent / HOBt, DCC / dimethylformamide / 1.) 30 min, -20 deg C; 2.) 0 deg C, 2 h; 3.) r.t., 18 h
3: di-tert-butyl sulfide / trifluoroacetic acid; H2O / 0.75 h / Ambient temperature
With
sulfure de di tert-butyle; hydrogen; benzotriazol-1-ol; dicyclohexyl-carbodiimide;
palladium on activated charcoal;
In
water; N,N-dimethyl-formamide; trifluoroacetic acid;
DOI:10.1002/recl.19831021101