1,2,4-Triazolo[4,3-a]pyridine,3-chloro-

Base Information

• Chemical Name: 1,2,4-Triazolo[4,3-a]pyridine,3-chloro-
• CAS No.: 4922-74-1
• Molecular Formula: C₆H₄ClN₃
• Molecular Weight: 153.571
• Hs Code.: 2933990090
• Mol file: 4922-74-1.mol

Synonyms:s-Triazolo[4,3-a]pyridine,3-chloro- (7CI,8CI); NSC 68463

Chemical Property of 1,2,4-Triazolo[4,3-a]pyridine,3-chloro-

Chemical Property:

• Melting Point: 125-127 °C(Solv: ethyl acetate (141-78-6))
• Boiling Point: °Cat760mmHg
• PKA: 1.05±0.50(Predicted)
• Flash Point: °C
• PSA: 30.19000
• Density: 1.51g/cm³
• LogP: 1.38270
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% purity ^*data from raw suppliers

3-Chloro-[1,2,4]triazolo[4,3-a]pyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2,4-Triazolo[4,3-a]pyridine,3-chloro-

There total 2 articles about 1,2,4-Triazolo[4,3-a]pyridine,3-chloro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

3-amino-s-triazolo-<4,3-a>-pyridne (767-62-4) → 3-Chlor-s-triazolo<4,3-a>pyridin (4922-74-1)

Guidance literature:

With pyrylium tetrafluoroborate; magnesium chloride; In acetonitrile; for 16h; Heating; Sealed tube;

DOI:10.1038/s41557-021-00812-0

Reference yield:

→ 3-Chlor-s-triazolo<4,3-a>pyridin (4922-74-1)

Guidance literature:

9, Cl2;

DOI:10.1021/jo00828a061

upstream raw materials:

3-amino-s-triazolo-<4,3-a>-pyridne

Refernces