BocS(OBzl)D(OBzl)OBzl

Base Information

• Chemical Name: BocS(OBzl)D(OBzl)OBzl
• CAS No.: 127103-15-5
• Molecular Formula: C₃₃H₃₈N₂O₈
• Molecular Weight: 590.673
• Mol file: 127103-15-5.mol

Synonyms:

Chemical Property of BocS(OBzl)D(OBzl)OBzl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of BocS(OBzl)D(OBzl)OBzl

There total 1 articles about BocS(OBzl)D(OBzl)OBzl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

BOC-O-benzyl-L-serine (23680-31-1) + dibenzyl L-aspartate toluene-4-sulphonate (2886-33-1) → BocS(OBzl)D(OBzl)OBzl (127103-15-5)

Guidance literature:

With 4-methyl-morpholine; isobutyl chloroformate; Yield given. Multistep reaction; 1.) THF, -15 deg C, 5 min, 2.) DMF, 1 h;

DOI:10.1021/jm00170a012

Reference yield:

BocS(OBzl)D(OBzl)OBzl (127103-15-5) + trifluoroacetic acid (76-05-1) → (S)-2-((S)-2-Amino-3-benzyloxy-propionylamino)-succinic acid dibenzyl ester; compound with trifluoro-acetic acid (129276-58-0)

Guidance literature:

In dichloromethane; for 2h; Ambient temperature;

DOI:10.1021/jm00170a012

Reference yield:

BocS(OBzl)D(OBzl)OBzl (127103-15-5) → N-L-seryl-L-aspartic acid (2543-31-9)

Guidance literature:

Multi-step reaction with 2 steps

1: CH₂Cl₂ / 2 h / Ambient temperature

2: H₂ / 10percent Pd/C / methanol; H₂O / 22 h / 760 Torr / Ambient temperature

With hydrogen; palladium on activated charcoal; In methanol; dichloromethane; water;

DOI:10.1021/jm00170a012

upstream raw materials:

BOC-O-benzyl-L-serine

dibenzyl L-aspartate toluene-4-sulphonate

Downstream raw materials:

(S)-2-((S)-2-Amino-3-benzyloxy-propionylamino)-succinic acid dibenzyl ester; compound with trifluoro-acetic acid

N-L-seryl-L-aspartic acid

Refernces