1,11-di(benzyloxy)-6,6-(2-oxapropane-1,3-diyl)-4,8-dioxaundecane

Base Information

• Chemical Name: 1,11-di(benzyloxy)-6,6-(2-oxapropane-1,3-diyl)-4,8-dioxaundecane
• CAS No.: 142731-79-1
• Molecular Formula: C₂₅H₃₄O₅
• Molecular Weight: 414.542
• Mol file: 142731-79-1.mol

Synonyms:

Chemical Property of 1,11-di(benzyloxy)-6,6-(2-oxapropane-1,3-diyl)-4,8-dioxaundecane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,11-di(benzyloxy)-6,6-(2-oxapropane-1,3-diyl)-4,8-dioxaundecane

There total 4 articles about 1,11-di(benzyloxy)-6,6-(2-oxapropane-1,3-diyl)-4,8-dioxaundecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,3-bis(hydroxymethyl)oxetane (2754-18-9) → 1,11-di(benzyloxy)-6,6-(2-oxapropane-1,3-diyl)-4,8-dioxaundecane (142731-79-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 65 percent / pyridine / CHCl₃ / 63 h

2: 90 percent / NaI / acetone

3: 1.) NaH / 1.) DMSO, 60 deg C, 4 h, 2.) DMSO, 60 deg C, overnight

With pyridine; sodium hydride; sodium iodide; In chloroform; acetone;

Reference yield:

3,3-bis-(toluene-4-sulfonyloxymethyl)-oxetane (6125-25-3) → 1,11-di(benzyloxy)-6,6-(2-oxapropane-1,3-diyl)-4,8-dioxaundecane (142731-79-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / NaI / acetone

2: 1.) NaH / 1.) DMSO, 60 deg C, 4 h, 2.) DMSO, 60 deg C, overnight

With sodium hydride; sodium iodide; In acetone;

Reference yield:

benzyl bromide (100-39-0) → 1,11-di(benzyloxy)-6,6-(2-oxapropane-1,3-diyl)-4,8-dioxaundecane (142731-79-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) NaH / 1.) THF, reflux, 5 h, 2.)THF, reflux, 3 d

2: 1.) NaH / 1.) DMSO, 60 deg C, 4 h, 2.) DMSO, 60 deg C, overnight

With sodium hydride;

upstream raw materials:

3,3-Bis(iodomethyl)oxacyclobutane

3-benzyloxypropan-1-ol

3,3-bis(hydroxymethyl)oxetane

3,3-bis-(toluene-4-sulfonyloxymethyl)-oxetane

Downstream raw materials:

11-tosyloxy-6,6-(2-oxapropane-1,3-diyl)-4,8-dioxa-1-undecanol

Refernces