Technology Process of 3-chloro-6-hexanoyl-7-hydroxyjuglone
There total 3 articles about 3-chloro-6-hexanoyl-7-hydroxyjuglone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 94 percent / MgCl2, pyridine / CH2Cl2
2: 2.) diisopropylamide, butyllithium / 1.) benzene, r.t.; 2.) hexane, THF, 0 deg C then -78 deg C to r.t.
3: 2.) silica gel / 1.) CH2Cl2, 0 deg C, 10 min then r.t., 1 h; 2.) CCl4
With
pyridine; n-butyllithium; silica gel; diisopropylamine; magnesium chloride;
In
dichloromethane;
DOI:10.1055/s-1994-25553
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 2.) diisopropylamide, butyllithium / 1.) benzene, r.t.; 2.) hexane, THF, 0 deg C then -78 deg C to r.t.
2: 2.) silica gel / 1.) CH2Cl2, 0 deg C, 10 min then r.t., 1 h; 2.) CCl4
With
n-butyllithium; silica gel; diisopropylamine;
DOI:10.1055/s-1994-25553
- Guidance literature:
-
With
silica gel;
Yield given. Multistep reaction;
1.) CH2Cl2, 0 deg C, 10 min then r.t., 1 h; 2.) CCl4;
DOI:10.1055/s-1994-25553
