p-chlorophenyl chloromethanesulfonate

Base Information

• Chemical Name: p-chlorophenyl chloromethanesulfonate
• CAS No.: 98274-02-3
• Molecular Formula: C₇H₆Cl₂O₃S
• Molecular Weight: 241.095
• Mol file: 98274-02-3.mol

Synonyms:

Chemical Property of p-chlorophenyl chloromethanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-chlorophenyl chloromethanesulfonate

There total 2 articles about p-chlorophenyl chloromethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-chlorophenyl mesylate (6317-27-7) → p-chlorophenyl chloromethanesulfonate (98274-02-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 47 percent / NaH / hexamethylphosphoric acid triamide / 1 h / Ambient temperature

2: 1.809 g / Et₃N, pyridine / 168 h / Ambient temperature

With pyridine; sodium hydride; triethylamine; In N,N,N,N,N,N-hexamethylphosphoric triamide;

Reference yield:

monochloromethanesulfonyl chloride (3518-65-8) + 4-chloro-phenol (106-48-9,82344-39-6) → p-chlorophenyl chloromethanesulfonate (98274-02-3)

Guidance literature:

With pyridine;

Reference yield: 28.0%

p-chlorophenyl chloromethanesulfonate (98274-02-3) → p-chlorophenyl dichloromethanesulfonate (152482-36-5)

Guidance literature:

With N-chloro-succinimide; sodium 4-chlorophenolate; In N,N,N,N,N,N-hexamethylphosphoric triamide; for 0.75h; Ambient temperature;

upstream raw materials:

monochloromethanesulfonyl chloride

4-chloro-phenol

p-chlorophenyl mesylate

Downstream raw materials:

p-chlorophenyl dichloromethanesulfonate

p-Tolylsulfanyl-methanesulfonic acid 4-chloro-phenyl ester

Refernces