N-(3,4-dihydroxyphenyl)benzamide

Base Information

• Chemical Name: N-(3,4-dihydroxyphenyl)benzamide
• CAS No.: 37519-15-6
• Molecular Formula: C₁₃H₁₁NO₃
• Molecular Weight: 229.235
• DSSTox Substance ID: DTXSID801302235
• Mol file: 37519-15-6.mol

Synonyms:SCHEMBL11793228;N-(3,4-dihydroxyphenyl)benzamide;DTXSID801302235;37519-15-6

Chemical Property of N-(3,4-dihydroxyphenyl)benzamide

Chemical Property:

• XLogP3: 2.5
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 229.07389321
• Heavy Atom Count: 17
• Complexity: 263

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)NC2=CC(=C(C=C2)O)O

Technology Process of N-(3,4-dihydroxyphenyl)benzamide

There total 8 articles about N-(3,4-dihydroxyphenyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-hydroxyphenyl benzoate (5876-92-6) → benzoic acid-(3,4-dihydroxy-anilide) (37519-15-6)

Guidance literature:

Multi-step reaction with 4 steps

2: aqueous ethanol; sodium dithionite

3: acetone; pyridine

4: aq.-ethanolic KOH-solution

With pyridine; potassium hydroxide; sodium dithionite; ethanol; acetone;

Reference yield:

benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9) → benzoic acid-(3,4-dihydroxy-anilide) (37519-15-6)

Guidance literature:

Multi-step reaction with 5 steps

1: aqueous sodium carbonate-solution; sodium dithionite

3: aqueous ethanol; sodium dithionite

4: acetone; pyridine

5: aq.-ethanolic KOH-solution

With pyridine; potassium hydroxide; sodium dithionite; ethanol; sodium carbonate; acetone;

Reference yield:

4-Benzoylamino-2-benzoyloxy-phenol → benzoic acid-(3,4-dihydroxy-anilide) (37519-15-6)

Guidance literature:

With potassium hydroxide;

upstream raw materials:

4-amino-pyrocatechol; hydrobromide

benzoyl chloride

2-hydroxyphenyl benzoate

2-Benzoyloxy-4-nitro-phenol

Downstream raw materials:

5,6-diacetoxy-2-phenyl-benzoxazole

2-phenyl-benzoxazole-5,6-diol

N-(3,4-dioxo-cyclohexa-1,5-dienyl)-benzamide