Silane, (1,1-dimethylethyl)[(2,2-dimethyl-5-nitro-1,3-dioxan-5-yl)methoxy]diphen yl-

Base Information

• Chemical Name: Silane, (1,1-dimethylethyl)[(2,2-dimethyl-5-nitro-1,3-dioxan-5-yl)methoxy]diphen yl-
• CAS No.: 138435-94-6
• Molecular Formula: C₂₃H₃₁NO₅Si
• Molecular Weight: 429.588
• Mol file: 138435-94-6.mol

Synonyms:

Chemical Property of Silane, (1,1-dimethylethyl)[(2,2-dimethyl-5-nitro-1,3-dioxan-5-yl)methoxy]diphen yl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Silane, (1,1-dimethylethyl)[(2,2-dimethyl-5-nitro-1,3-dioxan-5-yl)methoxy]diphen yl-

There total 1 articles about Silane, (1,1-dimethylethyl)[(2,2-dimethyl-5-nitro-1,3-dioxan-5-yl)methoxy]diphen yl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2-dimethyl-5-hydroxymethyl-5-nitro-1,3-dioxane (4728-14-7) + tert-butylchlorodiphenylsilane (58479-61-1) → 5-<<(tert-Butyldiphenylsilyl)oxy>methyl>-2,2-dimethyl-5-nitro-1,3-dioxane (138435-94-6)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; for 72h; Ambient temperature;

DOI:10.1021/jo00031a039

Reference yield:

5-<<(tert-Butyldiphenylsilyl)oxy>methyl>-2,2-dimethyl-5-nitro-1,3-dioxane (138435-94-6) → 2-(tert-Butyl-diphenyl-silanyloxymethyl)-2-nitro-propane-1,3-diol (138435-95-7)

Guidance literature:

With toluene-4-sulfonic acid; In methanol; for 1h; Ambient temperature;

DOI:10.1021/jo00031a039

Reference yield:

5-<<(tert-Butyldiphenylsilyl)oxy>methyl>-2,2-dimethyl-5-nitro-1,3-dioxane (138435-94-6) → 3-Acetoxy-2-(acetoxymethyl)-1-<(tert-butyldiphenylsilyl)oxy>propane (138435-87-7)

Guidance literature:

Multi-step reaction with 3 steps

1: p-toluenesulfonic acid hydrate / methanol / 1 h / Ambient temperature

2: 1.05 g / Et₃N, DMAP / CH₂Cl₂ / Ambient temperature

3: 63 percent / AIBN, Bu₃SnH / benzene / 6 h / Heating

With dmap; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; toluene-4-sulfonic acid; triethylamine; In methanol; dichloromethane; benzene;

DOI:10.1021/jo00031a039

upstream raw materials:

2,2-dimethyl-5-hydroxymethyl-5-nitro-1,3-dioxane

tert-butylchlorodiphenylsilane

Downstream raw materials:

2-(tert-Butyl-diphenyl-silanyloxymethyl)-2-nitro-propane-1,3-diol

3-Acetoxy-2-(acetoxymethyl)-1-<(tert-butyldiphenylsilyl)oxy>propane

3-Acetoxy-2-(acetoxymethyl)-1-<(tert-butyldiphenylsilyl)oxy>-2-nitropropane

Refernces