7(R)-Maresin 1

Base Information

• Chemical Name: 7(R)-Maresin 1
• CAS No.: 1268720-28-0
• Molecular Formula: C₂₂H₃₂O₄
• Molecular Weight: 360.494
• Mol file: 1268720-28-0.mol

Synonyms:

Chemical Property of 7(R)-Maresin 1

Chemical Property:

• Boiling Point: 559.4±50.0 °C(Predicted)
• PKA: 4.58±0.10(Predicted)
• Density: 1.048±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

Maresin 1 ≥95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7(R)-Maresin 1

There total 45 articles about 7(R)-Maresin 1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

C34H60O4Si2 (1268720-46-2) → maresin 1 (1268720-28-0)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.1002/asia.201000494

Reference yield: 81.0%

ethyl (4Z,7R,8E,10E,12Z,14S,16Z,19Z)-7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoate → maresin 1 (1268720-28-0)

Guidance literature:

With water; lithium hydroxide; In tetrahydrofuran; methanol; at 0 ℃; for 3h;

DOI:10.1016/j.tetlet.2015.02.080

Reference yield: 77.0%

maresin 1 methyl ester (1391043-18-7) → maresin 1 (1268720-28-0)

Guidance literature:

maresin 1 methyl ester; With lithium hydroxide; In methanol; water; at 0 ℃; for 24h;

With sodium dihydrogenphosphate; In methanol; water; ethyl acetate; Saturated solution;

DOI:10.1016/j.tetlet.2012.05.143

upstream raw materials:

C₂₀H₃₄O₂Si

C₂₀H₃₆O₂Si

C₂₇H₃₉NOS₂Si

C₂₇H₃₉NO₃S₂Si

Refernces

• 1、 Tungen, J?rn E.,Aursnes, Marius,Hansen, Trond Vidar. "Stereoselective synthesis of maresin 1". supporting information. p. 1843 - 1846. Retrieved 2015/03/30.