Technology Process of C21H15F3N4O2
There total 5 articles about C21H15F3N4O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: caesium carbonate / N,N-dimethyl-formamide / 3 h
2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / 1,2-dimethoxyethane; ethanol; water / 0.33 h / 160 °C / Microwave irradiation
3: hydrazine hydrate; toluene-4-sulfonic acid / 0.33 h / 130 °C
4: N,N-dimethyl-formamide / 4 h
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; hydrazine hydrate; sodium carbonate; caesium carbonate; toluene-4-sulfonic acid;
In
1,2-dimethoxyethane; ethanol; water; N,N-dimethyl-formamide;
2: Suzuki coupling;
DOI:10.1016/j.bmcl.2012.06.009
- Guidance literature:
-
Multi-step reaction with 3 steps
1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / 1,2-dimethoxyethane; ethanol; water / 0.33 h / 160 °C / Microwave irradiation
2: hydrazine hydrate; toluene-4-sulfonic acid / 0.33 h / 130 °C
3: N,N-dimethyl-formamide / 4 h
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; hydrazine hydrate; sodium carbonate; toluene-4-sulfonic acid;
In
1,2-dimethoxyethane; ethanol; water; N,N-dimethyl-formamide;
1: Suzuki coupling;
DOI:10.1016/j.bmcl.2012.06.009
- Guidance literature:
-
Multi-step reaction with 2 steps
1: hydrazine hydrate; toluene-4-sulfonic acid / 0.33 h / 130 °C
2: N,N-dimethyl-formamide / 4 h
With
hydrazine hydrate; toluene-4-sulfonic acid;
In
N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2012.06.009