(Z)-p-methoxyphenyl-2 epoxy-1,2 ethanephosphonate

Base Information

• Chemical Name: (Z)-p-methoxyphenyl-2 epoxy-1,2 ethanephosphonate
• CAS No.: 123098-29-3
• Molecular Formula: C₁₃H₁₉O₅P
• Molecular Weight: 286.265
• Mol file: 123098-29-3.mol

Synonyms:

Chemical Property of (Z)-p-methoxyphenyl-2 epoxy-1,2 ethanephosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-p-methoxyphenyl-2 epoxy-1,2 ethanephosphonate

There total 8 articles about (Z)-p-methoxyphenyl-2 epoxy-1,2 ethanephosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

diethyl (dichloromethyl)phosphonate (3167-62-2) + 4-methoxy-benzaldehyde (123-11-5) → diethyl chloromethylphosphonate (3167-63-3) + 1-[2-chloroethenyl]-4-methoxybenzene (477727-71-2) + p-methoxyphenyl-2 epoxy-1,2 ethanephosphonate (123098-29-3,123098-30-6) + 4-methoxyphenylacetylen (768-60-5)

Guidance literature:

With benzophenone; tetrabutylammonium tetrafluoroborate; In N,N-dimethyl-formamide; Ambient temperature; controlled potential electrolysis; cathode: Hg; electrode ref.: AgI/Ag;

Reference yield:

diethyl (trichloromethyl)phosphonate (866-23-9) → (E)-p-methoxyphenyl-2 epoxy-1,2 ethanephosphonate (123098-29-3,123098-30-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 30 percent / p-methoxybenzaldehyde, Bu₄NBF₄ / dimethylformamide / Ambient temperature; controlled potential electrolysis; cathode: Hg; electrode ref.: AgI/Ag

2: 42 percent / Me₄NBF₄ / dimethylformamide / Ambient temperature; controlled potential electrolysis; cathode: Hg; electrode ref.: AgI/Ag

3: Me₄NBF₄, azobenzene / dimethylformamide / Ambient temperature; controlled potential electrolysis; cathode: Hg; electrode ref.: AgI/Ag

With tetrabutylammonium tetrafluoroborate; tetramethylammonium tetrafluoroborate; 4-methoxy-benzaldehyde; Azobenzene; In N,N-dimethyl-formamide;

Reference yield:

diethyl (trichloromethyl)phosphonate (866-23-9) → (Z)-p-methoxyphenyl-2 epoxy-1,2 ethanephosphonate (123098-29-3,123098-30-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 30 percent / p-methoxybenzaldehyde, Bu₄NBF₄ / dimethylformamide / Ambient temperature; controlled potential electrolysis; cathode: Hg; electrode ref.: AgI/Ag

2: 42 percent / Me₄NBF₄ / dimethylformamide / Ambient temperature; controlled potential electrolysis; cathode: Hg; electrode ref.: AgI/Ag

3: Me₄NBF₄, azobenzene / dimethylformamide / Ambient temperature; controlled potential electrolysis; cathode: Hg; electrode ref.: AgI/Ag

With tetrabutylammonium tetrafluoroborate; tetramethylammonium tetrafluoroborate; 4-methoxy-benzaldehyde; Azobenzene; In N,N-dimethyl-formamide;

upstream raw materials:

diethyl (dichloromethyl)phosphonate

4-methoxy-benzaldehyde

diethyl (trichloromethyl)phosphonate

diethyl chloromethylphosphonate

Refernces