C₃₁H₃₈Br₂NO₅⁽¹⁺⁾*I^(1-)

Base Information

• Chemical Name: C₃₁H₃₈Br₂NO₅⁽¹⁺⁾*I^(1-)
• CAS No.: 1403649-85-3
• Molecular Formula: C₃₁H₃₈Br₂NO₅*I
• Molecular Weight: 791.359
• Mol file: 1403649-85-3.mol

Synonyms:

Chemical Property of C₃₁H₃₈Br₂NO₅⁽¹⁺⁾*I^(1-)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₁H₃₈Br₂NO₅⁽¹⁺⁾*I^(1-)

There total 8 articles about C₃₁H₃₈Br₂NO₅⁽¹⁺⁾*I^(1-) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C16H29NO3 → C31H38Br2NO5(1+)*I(1-) (1403649-85-3)

Guidance literature:

Multi-step reaction with 2 steps

1: dmap; triethylamine / dichloromethane

2: potassium carbonate / acetonitrile / 5 h

With dmap; potassium carbonate; triethylamine; In dichloromethane; acetonitrile;

DOI:10.1002/anie.201204274

Reference yield:

diethyl 2-((tetrahydrofuran-2-yl)methyl)malonate (37136-39-3) → C31H38Br2NO5(1+)*I(1-) (1403649-85-3)

Guidance literature:

Multi-step reaction with 8 steps

1.1: sodium hydride / N,N-dimethyl-formamide; toluene / 0.5 h / 20 °C / Inert atmosphere

1.2: 0.5 h / Inert atmosphere

2.1: potassium carbonate / methanol / 1 h

3.1: Dess-Martin periodane / dichloromethane / 20 °C / Inert atmosphere

4.1: silver hexafluoroantimonate; (2R,5R)-5-benzyl-2-tert-butyl-3-methyl-imidazolidin-4-one hydrochloride / chloroform / 20 °C / Inert atmosphere

5.1: NaBH(OAc)3 / 1,2-dichloro-ethane / 20 °C / Inert atmosphere

6.1: lithium aluminium tetrahydride / tetrahydrofuran / 5 h / 20 °C / Inert atmosphere

7.1: dmap; triethylamine / dichloromethane

8.1: potassium carbonate / acetonitrile / 5 h

With dmap; silver hexafluoroantimonate; lithium aluminium tetrahydride; (2R,5R)-5-benzyl-2-tert-butyl-3-methyl-imidazolidin-4-one hydrochloride; NaBH(OAc)3; sodium hydride; potassium carbonate; Dess-Martin periodane; triethylamine; In tetrahydrofuran; methanol; dichloromethane; chloroform; 1,2-dichloro-ethane; N,N-dimethyl-formamide; toluene; acetonitrile; 4.1: Prins reaction;

DOI:10.1002/anie.201204274

Reference yield:

C16H24O6 (1403649-83-1) → C31H38Br2NO5(1+)*I(1-) (1403649-85-3)

Guidance literature:

Multi-step reaction with 4 steps

1: NaBH(OAc)3 / 1,2-dichloro-ethane / 20 °C / Inert atmosphere

2: lithium aluminium tetrahydride / tetrahydrofuran / 5 h / 20 °C / Inert atmosphere

3: dmap; triethylamine / dichloromethane

4: potassium carbonate / acetonitrile / 5 h

With dmap; lithium aluminium tetrahydride; NaBH(OAc)3; potassium carbonate; triethylamine; In tetrahydrofuran; dichloromethane; 1,2-dichloro-ethane; acetonitrile;

DOI:10.1002/anie.201204274

upstream raw materials:

methyl iodide

C₁₆H₂₄O₆

C₂₀H₃₃NO₅

diethyl 2-((tetrahydrofuran-2-yl)methyl)malonate

Refernces