3,8-dihydroxyoctanoic acid

Base Information

• Chemical Name: 3,8-dihydroxyoctanoic acid
• CAS No.: 692-15-9
• Molecular Formula: C₈H₁₆O₄
• Molecular Weight: 176.213
• Mol file: 692-15-9.mol

Synonyms:NSC 280691;

Chemical Property of 3,8-dihydroxyoctanoic acid

Chemical Property:

• Vapor Pressure: 8.83E-08mmHg at 25°C
• Refractive Index: 1.492
• Boiling Point: 392.3 °C at 760 mmHg
• Flash Point: 205.2 °C
• Density: 1.17 g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,8-dihydroxyoctanoic acid

There total 2 articles about 3,8-dihydroxyoctanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-Keto-8-hydroxy-octansaeure-nitril (762-34-5) → 3,8-Dihydroxy-octansaeure (692-15-9)

Guidance literature:

Multistep reaction; (i) aq. NaBH₄, MeOH, (ii) aq. KOH, EtOH;

DOI:10.1021/jo01035a017

Reference yield:

hexahydro-2H-oxepin-2-one (502-44-3,24980-41-4,80137-66-2) → 3,8-Dihydroxy-octansaeure (692-15-9)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) NaNH₂, liq. NH₃, Et₂O, (ii) /BRN= 106919/

2: (i) aq. NaBH₄, MeOH, (ii) aq. KOH, EtOH

DOI:10.1021/jo01035a017

Reference yield:

3,8-Dihydroxy-octansaeure (692-15-9) → trans-8-Hydroxy-oct-2-ensaeure (68750-26-5,764-90-9)

Guidance literature:

Multistep reaction; (i) Ac₂O, (ii) KOH, EtOH;

DOI:10.1021/jo01035a017

upstream raw materials:

3-Keto-8-hydroxy-octansaeure-nitril

hexahydro-2H-oxepin-2-one

Downstream raw materials:

trans-8-Hydroxy-oct-2-ensaeure