Ethyl 3-broMo-5-chloroisonicotinate

Base Information

• Chemical Name: Ethyl 3-broMo-5-chloroisonicotinate
• CAS No.: 1214387-79-7
• Molecular Formula: C₈H₇BrClNO₂
• Molecular Weight: 264.506
• Mol file: 1214387-79-7.mol

Synonyms:

Chemical Property of Ethyl 3-broMo-5-chloroisonicotinate

Chemical Property:

Purity/Quality:

95+% ^*data from raw suppliers

Ethyl3-bromo-5-chloroisonicotinate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ethyl 3-broMo-5-chloroisonicotinate

There total 1 articles about Ethyl 3-broMo-5-chloroisonicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

3-bromo-5-chloropyridine (73583-39-8) + chloroformic acid ethyl ester (541-41-3) → ethyl 3-bromo-5-chloropyridine-4-carboxylate (1214387-79-7)

Guidance literature:

3-bromo-5-chloropyridine; With lithium diisopropyl amide; In tetrahydrofuran; n-heptane; ethylbenzene; at -78 ℃; for 0.75h; Inert atmosphere;

chloroformic acid ethyl ester; In tetrahydrofuran; n-heptane; ethylbenzene; for 0.583333h;

With sodium hydrogencarbonate; In tetrahydrofuran; n-heptane; ethylbenzene; Product distribution / selectivity;

upstream raw materials:

3-bromo-5-chloropyridine

chloroformic acid ethyl ester

Refernces

• 1、 -. "METHYL SULFANYL PYRMIDMES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS". Page/Page column 161; 163; 212. . Retrieved 2010/12/18.