clionasterol benzoate

Base Information

• Chemical Name: clionasterol benzoate
• CAS No.: 18777-86-1
• Molecular Formula: C₃₆H₅₄O₂
• Molecular Weight: 518.824
• Mol file: 18777-86-1.mol

Synonyms:

Chemical Property of clionasterol benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of clionasterol benzoate

There total 18 articles about clionasterol benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

clionasterol (83-46-5,83-47-6,5779-62-4,19044-06-5,31793-83-6,125636-84-2,130062-49-6) + benzoyl chloride (98-88-4) → clionasterol benzoate (18777-86-1)

Guidance literature:

With pyridine;

DOI:10.1021/jo01203a011 DOI:10.1021/ja01854a037 DOI:10.1021/jo01164a014

Reference yield:

Benzoic acid (3S,8S,9S,10R,13R,14S)-17-((1R,4R)-4-isopropyl-1-methyl-5-phenoxythiocarbonyloxy-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester (101047-07-8,112573-50-9,112573-51-0,112573-52-1,112573-53-2) → fucosterol benzoate (6035-63-8,72317-98-7,77698-79-4,108814-73-9) + clionasterol benzoate (1900-52-3,18777-86-1)

Guidance literature:

With tri-n-butyl-tin hydride; In toluene; at 130 ℃; for 5h;

Reference yield:

3β-acetoxysitosterol (4651-54-1) → clionasterol benzoate (18777-86-1)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanolic KOH

2: pyridine

With pyridine; potassium hydroxide;

DOI:10.1021/jo01203a011 DOI:10.1021/ja01854a037

upstream raw materials:

clionasterol

benzoyl chloride

(24S)-24-isopropenylcholest-5-en-3β-ol

24S-isopropenylcholesterol benzoate

Refernces

• 1、 Kadota, Shigetoshi,Shima, Takehiko,Kikuchi, Tohru. "Studies on the Constituents of Orchidaceous Plants. VII. The C-24 Stereochemistry of Cyclohomonervilol and 24-Isopropenylcholesterol, Non-conventional Side Chain Triterpene and Sterol, from Nervilia purpurea SCHLECHTER". . p. 200 - 210. Retrieved 2007/10/02.
• 2、 Joshi,Prakash,Shah. "Chemical constituents of Clerodendron infortunatum Linn. and Ficus racemosa Linn.". . p. 1104 - 1104. Retrieved 2007/10/06.