4-nitro-benzoic acid-(2,3,4,5,6-pentafluoro-benzyl ester)

Base Information

• Chemical Name: 4-nitro-benzoic acid-(2,3,4,5,6-pentafluoro-benzyl ester)
• CAS No.: 362-49-2
• Molecular Formula: C₁₄H₆F₅NO₄
• Molecular Weight: 347.198
• Mol file: 362-49-2.mol

Synonyms:

Chemical Property of 4-nitro-benzoic acid-(2,3,4,5,6-pentafluoro-benzyl ester)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-nitro-benzoic acid-(2,3,4,5,6-pentafluoro-benzyl ester)

There total 8 articles about 4-nitro-benzoic acid-(2,3,4,5,6-pentafluoro-benzyl ester) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Pentafluorobenzoic acid (602-94-8) → 4-nitro-benzoic acid-(2,3,4,5,6-pentafluoro-benzyl ester) (362-49-2)

Guidance literature:

With hydrogenchloride; lithium aluminium tetrahydride; 4-nitro-benzoyl chloride;

DOI:10.1021/ja01147a520

Reference yield:

perfluorotoluene (434-64-0) → 4-nitro-benzoic acid-(2,3,4,5,6-pentafluoro-benzyl ester) (362-49-2)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂SO₄

2: LiAlH₄; aqueous HCl; 4-nitro-benzoyl chloride

With hydrogenchloride; lithium aluminium tetrahydride; sulfuric acid; 4-nitro-benzoyl chloride;

DOI:10.1021/ja01147a520

Reference yield:

bromopentafluorobenzene (344-04-7) → 4-nitro-benzoic acid-(2,3,4,5,6-pentafluoro-benzyl ester) (362-49-2)

Guidance literature:

Multi-step reaction with 3 steps

1: (i) Mg, (ii) /BRN= 636496/

2: LiAlH₄

With lithium aluminium tetrahydride;

DOI:10.1039/jr9610000808

upstream raw materials:

Pentafluorobenzoic acid

(2,3,4,5,6-pentafluorophenyl)methanol

4-nitro-benzoyl chloride

perfluorotoluene