N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(4-((phenylthio)carbonyl)butyl)-N-(phenylmethoxy)butanediamide

Base Information

• Chemical Name: N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(4-((phenylthio)carbonyl)butyl)-N-(phenylmethoxy)butanediamide
• CAS No.: 123152-42-1
• Molecular Formula: C₅₂H₆₇N₅O₉S
• Molecular Weight: 938.198
• Mol file: 123152-42-1.mol

Synonyms:

Chemical Property of N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(4-((phenylthio)carbonyl)butyl)-N-(phenylmethoxy)butanediamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(4-((phenylthio)carbonyl)butyl)-N-(phenylmethoxy)butanediamide

There total 4 articles about N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(4-((phenylthio)carbonyl)butyl)-N-(phenylmethoxy)butanediamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(4-cyanobutyl)-N-(phenylmethoxy)butanediamide (112139-65-8) → N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(4-((phenylthio)carbonyl)butyl)-N-(phenylmethoxy)butanediamide (123152-42-1)

Guidance literature:

Multi-step reaction with 4 steps

1: HCl (gas) / 20 h / -20 °C

2: H₂O / 6 h / 0 °C

3: 55 percent / aq. KOH / acetone / Ambient temperature

4: dicyclohexylcarbodiimide (DCC), (dimethylamino)pyridine / CH₂Cl₂ / Ambient temperature

With hydrogenchloride; dmap; potassium hydroxide; water; dicyclohexyl-carbodiimide; In dichloromethane; acetone;

DOI:10.1021/jo00284a044

Reference yield:

N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(4-(ethoxycarbonyl)butyl)-N-(phenylmethoxy)butanediamide (123152-40-9) → N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(4-((phenylthio)carbonyl)butyl)-N-(phenylmethoxy)butanediamide (123152-42-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 55 percent / aq. KOH / acetone / Ambient temperature

2: dicyclohexylcarbodiimide (DCC), (dimethylamino)pyridine / CH₂Cl₂ / Ambient temperature

With dmap; potassium hydroxide; dicyclohexyl-carbodiimide; In dichloromethane; acetone;

DOI:10.1021/jo00284a044

Reference yield:

N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(5-ethoxy-5-iminopentyl)-N-(phenylmethoxy)butanediamide hydrochloride (123152-39-6) → N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(4-((phenylthio)carbonyl)butyl)-N-(phenylmethoxy)butanediamide (123152-42-1)

Guidance literature:

Multi-step reaction with 3 steps

1: H₂O / 6 h / 0 °C

2: 55 percent / aq. KOH / acetone / Ambient temperature

3: dicyclohexylcarbodiimide (DCC), (dimethylamino)pyridine / CH₂Cl₂ / Ambient temperature

With dmap; potassium hydroxide; water; dicyclohexyl-carbodiimide; In dichloromethane; acetone;

DOI:10.1021/jo00284a044

upstream raw materials:

thiophenol

N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(4-carboxybutyl)-N-(phenylmethoxy)butanediamide

N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(4-cyanobutyl)-N-(phenylmethoxy)butanediamide

N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(4-(ethoxycarbonyl)butyl)-N-(phenylmethoxy)butanediamide

Downstream raw materials:

N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(5-hydroxypentyl)-N-(phenylmethoxy)butanediamide

Refernces