Technology Process of 3-<3-<3-(guanidinoacetamido)benzamido>benzamido>benzamidopropionitrile hydrochloride
There total 7 articles about 3-<3-<3-(guanidinoacetamido)benzamido>benzamido>benzamidopropionitrile hydrochloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: SOCl2
2: 82 percent / 4percent aq. NaHCO3 / acetone / 12 h / Ambient temperature
3: SOCl2
5: 65 percent / H2 / 10percent Pd/C / dimethylformamide; methanol / 760 Torr / Ambient temperature
6: 53 percent / DCC / dimethylsulfoxide / 12 h / Ambient temperature
With
thionyl chloride; hydrogen; sodium hydrogencarbonate; dicyclohexyl-carbodiimide;
palladium on activated charcoal;
In
methanol; dimethyl sulfoxide; N,N-dimethyl-formamide; acetone;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 82 percent / 4percent aq. NaHCO3 / acetone / 12 h / Ambient temperature
2: SOCl2
4: 65 percent / H2 / 10percent Pd/C / dimethylformamide; methanol / 760 Torr / Ambient temperature
5: 53 percent / DCC / dimethylsulfoxide / 12 h / Ambient temperature
With
thionyl chloride; hydrogen; sodium hydrogencarbonate; dicyclohexyl-carbodiimide;
palladium on activated charcoal;
In
methanol; dimethyl sulfoxide; N,N-dimethyl-formamide; acetone;
- Guidance literature:
-
Multi-step reaction with 3 steps
2: 65 percent / H2 / 10percent Pd/C / dimethylformamide; methanol / 760 Torr / Ambient temperature
3: 53 percent / DCC / dimethylsulfoxide / 12 h / Ambient temperature
With
hydrogen; dicyclohexyl-carbodiimide;
palladium on activated charcoal;
In
methanol; dimethyl sulfoxide; N,N-dimethyl-formamide;
