N^ω-nitro-N^α-(4-nitro-benzyloxycarbonyl)-L-arginine

Base Information

• Chemical Name: N^ω-nitro-N^α-(4-nitro-benzyloxycarbonyl)-L-arginine
• CAS No.: 183659-61-2
• Molecular Formula: C₁₄H₁₈N₆O₈
• Molecular Weight: 398.332
• Mol file: 183659-61-2.mol

Synonyms:

Chemical Property of N^ω-nitro-N^α-(4-nitro-benzyloxycarbonyl)-L-arginine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N^ω-nitro-N^α-(4-nitro-benzyloxycarbonyl)-L-arginine

There total 1 articles about N^ω-nitro-N^α-(4-nitro-benzyloxycarbonyl)-L-arginine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-nitro-L-arginine (2149-70-4,13855-78-2,38733-00-5) + 4-nitrobenzyl chloroformate (4457-32-3) → Nω-nitro-Nα-(4-nitro-benzyloxycarbonyl)-L-arginine (183659-61-2)

Guidance literature:

With tetrahydrofuran; sodium hydroxide;

DOI:10.1021/jo01113a610

Reference yield:

Nω-nitro-Nα-(4-nitro-benzyloxycarbonyl)-L-arginine (183659-61-2) → L-Arg-Gly (2418-67-9)

Guidance literature:

Multi-step reaction with 3 steps

1: chlorocarbonic acid ethyl ester; tributylamine; THF / anschliessend Behandeln mit Glycin-aethylester

2: methanol; aqueous NaOH

3: palladium/charcoal; ethanol; acetic acid

With tetrahydrofuran; methanol; sodium hydroxide; palladium on activated charcoal; tributyl-amine; ethanol; chloroformic acid ethyl ester; acetic acid;

DOI:10.1021/jo01113a610

Reference yield:

Nω-nitro-Nα-(4-nitro-benzyloxycarbonyl)-L-arginine (183659-61-2) → Nω-nitro-Nα-(4-nitro-benzyloxycarbonyl)-L-arginine anilide (103509-13-3)

Guidance literature:

With tributyl-amine; chloroformic acid ethyl ester; anschliessendes Behandeln mit Anilin;

DOI:10.1021/jo01113a610

upstream raw materials:

N-nitro-L-arginine

4-nitrobenzyl chloroformate

Downstream raw materials:

N^ω-nitro-N^α-(4-nitro-benzyloxycarbonyl)-L-arginine anilide

N-[N^ω-nitro-N^α-(4-nitro-benzyloxycarbonyl)-L-arginyl]-glycine ethyl ester

N-[N^ω-nitro-N^α-(4-nitro-benzyloxycarbonyl)-L-arginyl]-L-leucine ethyl ester

N-[N^ω-nitro-N^α-(4-nitro-benzyloxycarbonyl)-L-arginyl]-L-glutamic acid diethyl ester