Technology Process of [2-methyl-4-([1,1';3',1'']terphenyl-5'-ylmethoxy)-phenoxy]-acetic acid methyl ester
There total 5 articles about [2-methyl-4-([1,1';3',1'']terphenyl-5'-ylmethoxy)-phenoxy]-acetic acid methyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0); potassium carbonate;
In
1,4-dioxane; ethanol;
at 170 ℃;
for 0.166667h;
microwave irradiation;
DOI:10.1016/j.bmcl.2006.02.079
- Guidance literature:
-
Multi-step reaction with 5 steps
1: Cs2CO3 / acetonitrile / 20 °C
2: meta-chloroperbenzoic acid; p-TsOH / CH2Cl2 / 48 h / Heating
3: MeONa / methanol / 1 h / 20 °C
4: 95 percent / Cs2CO3 / acetonitrile / 18 h / 20 °C
5: aq. K2CO3; Pd(Ph3P)4 / ethanol; dioxane / 0.17 h / 170 °C / microwave irradiation
With
tetrakis(triphenylphosphine) palladium(0); sodium methylate; potassium carbonate; caesium carbonate; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid;
In
1,4-dioxane; methanol; ethanol; dichloromethane; acetonitrile;
5: Suzuki coupling;
DOI:10.1016/j.bmcl.2006.02.079
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 95 percent / Cs2CO3 / acetonitrile / 18 h / 20 °C
2: aq. K2CO3; Pd(Ph3P)4 / ethanol; dioxane / 0.17 h / 170 °C / microwave irradiation
With
tetrakis(triphenylphosphine) palladium(0); potassium carbonate; caesium carbonate;
In
1,4-dioxane; ethanol; acetonitrile;
2: Suzuki coupling;
DOI:10.1016/j.bmcl.2006.02.079