N-(3-(1H-pyrrol-1-yl)phenyl)acetamide

Base Information

• Chemical Name: N-(3-(1H-pyrrol-1-yl)phenyl)acetamide
• CAS No.: 184097-44-7
• Molecular Formula: C₁₂H₁₂N₂O
• Molecular Weight: 200.24
• Mol file: 184097-44-7.mol

Synonyms:

Chemical Property of N-(3-(1H-pyrrol-1-yl)phenyl)acetamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(3-(1H-pyrrol-1-yl)phenyl)acetamide

There total 3 articles about N-(3-(1H-pyrrol-1-yl)phenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C12H14N2O → N-(3-(1H-pyrrol-1-yl)phenyl)acetamide (184097-44-7)

Guidance literature:

With tert.-butylhydroperoxide; In water; ethyl acetate; at 20 ℃; for 0.5h; Inert atmosphere;

DOI:10.1039/c2ob25543j

Reference yield:

m-acetamide aniline (102-28-3) → N-(3-(1H-pyrrol-1-yl)phenyl)acetamide (184097-44-7)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium carbonate / ethanol; water / 80 °C / Inert atmosphere

2: Grubbs catalyst first generation / ethyl acetate / 0.5 h / 20 °C / Inert atmosphere

3: tert.-butylhydroperoxide / water; ethyl acetate / 0.5 h / 20 °C / Inert atmosphere

With Grubbs catalyst first generation; tert.-butylhydroperoxide; sodium carbonate; In ethanol; water; ethyl acetate;

DOI:10.1039/c2ob25543j

Reference yield:

N-(3-(diallylamino)phenyl)acetamide (69962-41-0) → N-(3-(1H-pyrrol-1-yl)phenyl)acetamide (184097-44-7)

Guidance literature:

Multi-step reaction with 2 steps

1: Grubbs catalyst first generation / ethyl acetate / 0.5 h / 20 °C / Inert atmosphere

2: tert.-butylhydroperoxide / water; ethyl acetate / 0.5 h / 20 °C / Inert atmosphere

With Grubbs catalyst first generation; tert.-butylhydroperoxide; In water; ethyl acetate;

DOI:10.1039/c2ob25543j

upstream raw materials:

N-(3-(diallylamino)phenyl)acetamide

m-acetamide aniline

Refernces