C₂₂H₁₉N₃O₂

Base Information

• Chemical Name: C₂₂H₁₉N₃O₂
• CAS No.: 1351520-10-9
• Molecular Formula: C₂₂H₁₉N₃O₂
• Molecular Weight: 357.412
• Mol file: 1351520-10-9.mol

Synonyms:

Chemical Property of C₂₂H₁₉N₃O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₁₉N₃O₂

There total 7 articles about C₂₂H₁₉N₃O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(2’,4’,6’-trimethylanilido)nitrobenzene (28458-49-3) → C22H19N3O2 (1351520-10-9)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium dithionite / ethyl methyl ether; water / 24 h / 100 °C

2: selenium(IV) oxide / 1,4-dioxane / 24 h / 110 °C

3: formic acid; dihydrogen peroxide / 0 °C

With selenium(IV) oxide; formic acid; sodium dithionite; dihydrogen peroxide; In 1,4-dioxane; ethyl methyl ether; water;

DOI:10.1002/adsc.201100210

Reference yield:

2.6-bis(hydroxymethyl)pyridine (1195-59-1) → C22H19N3O2 (1351520-10-9)

Guidance literature:

Multi-step reaction with 4 steps

1: selenium(IV) oxide / 1,4-dioxane / 48 h / 65 °C / Inert atmosphere; Ultrasonic bath

2: sodium dithionite / ethyl methyl ether; water / 24 h / 100 °C

3: selenium(IV) oxide / 1,4-dioxane / 24 h / 110 °C

4: formic acid; dihydrogen peroxide / 0 °C

With selenium(IV) oxide; formic acid; sodium dithionite; dihydrogen peroxide; In 1,4-dioxane; ethyl methyl ether; water;

DOI:10.1002/adsc.201100210

Reference yield:

ortho-nitrofluorobenzene (1493-27-2,127723-77-7) → C22H19N3O2 (1351520-10-9)

Guidance literature:

Multi-step reaction with 4 steps

1: potassium fluoride / 48 h / 180 °C / Inert atmosphere

2: sodium dithionite / ethyl methyl ether; water / 24 h / 100 °C

3: selenium(IV) oxide / 1,4-dioxane / 24 h / 110 °C

4: formic acid; dihydrogen peroxide / 0 °C

With selenium(IV) oxide; potassium fluoride; formic acid; sodium dithionite; dihydrogen peroxide; In 1,4-dioxane; ethyl methyl ether; water;

DOI:10.1002/adsc.201100210

upstream raw materials:

6-(hydroxymethyl)picolinaldehyde

2.6-bis(hydroxymethyl)pyridine

C₂₂H₂₁N₃O

C₂₂H₁₉N₃O

Refernces