9,9'-Spirobi[9H-fluorene]-4-ylboronicacid

Base Information

• Chemical Name: 9,9'-Spirobi[9H-fluorene]-4-ylboronicacid
• CAS No.: 1421789-05-0
• Molecular Formula: C₂₅H₁₇BO₂
• Molecular Weight: 360.22
• Mol file: 1421789-05-0.mol

Synonyms:

Chemical Property of 9,9'-Spirobi[9H-fluorene]-4-ylboronicacid

Chemical Property:

• Boiling Point: 588.4±60.0 °C(Predicted)
• PKA: 8.22±0.20(Predicted)
• Density: 1.37±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

9,9'-Spirobi[fluoren]-4-ylboronicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 9,9'-Spirobi[9H-fluorene]-4-ylboronicacid

There total 9 articles about 9,9'-Spirobi[9H-fluorene]-4-ylboronicacid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

Triisopropyl borate (5419-55-6) + 4-bromo-9,9’-spirobi[9H-fluorene] (1161009-88-6) + water (7732-18-5) → (9,9'-spirobi[9H-fluoren]-4-yl)boronic acid (1421789-05-0)

Guidance literature:

Triisopropyl borate; 4-bromo-9,9’-spirobi[9H-fluorene]; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 5h;

water; With hydrogenchloride; In tetrahydrofuran;

Reference yield: 81.0%

Trimethyl borate (121-43-7,63156-11-6) + 4-bromo-9,9’-spirobi[9H-fluorene] (1161009-88-6) → (9,9'-spirobi[9H-fluoren]-4-yl)boronic acid (1421789-05-0)

Guidance literature:

4-bromo-9,9’-spirobi[9H-fluorene]; With n-butyllithium; In tetrahydrofuran; at -78 - 0 ℃; for 1h;

Trimethyl borate; In tetrahydrofuran; at -78 - 20 ℃; for 12h;

With hydrogenchloride; In tetrahydrofuran; water; for 0.5h;

Reference yield: 81.0%

→ (9,9'-spirobi[9H-fluoren]-4-yl)boronic acid (1421789-05-0)

Guidance literature:

With n-butyllithium; In diethyl ether; at -78 ℃; for 0.5h;

With hydrogenchloride; In diethyl ether; water; at -78 - -10 ℃;

upstream raw materials:

2-iodobiphenyl

Trimethyl borate

4-bromo-9,9’-spirobi[9H-fluorene]

4-bromo-9H-fluorene-9-one

Refernces

• 1、 -. "ANTHRACENE BASED COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME". Paragraph 0225; 0226. . Retrieved 2018/05/03.
• 2、 -. "A 9,9 the [...] -Spirobifluorene-4-boronic acid synthesis method". Paragraph 0025; 0028. . Retrieved 2017/04/05.