C₁₈H₂₁N₃O₇S₂

Base Information

• Chemical Name: C₁₈H₂₁N₃O₇S₂
• CAS No.: 231607-41-3
• Molecular Formula: C₁₈H₂₁N₃O₇S₂
• Molecular Weight: 455.513
• Mol file: 231607-41-3.mol

Synonyms:

Chemical Property of C₁₈H₂₁N₃O₇S₂

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₈H₂₁N₃O₇S₂

There total 6 articles about C₁₈H₂₁N₃O₇S₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2R,3R)-2,3-dihydroxy-4-{[(4-methylphenyl)sulfonyl]oxy}butyl 4-methyl-1-benzenesulfonate (50623-73-9,68138-99-8) → C18H21N3O7S2 (231607-41-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 96 percent / SOCl₂ / CH₂Cl₂ / 18 h / 20 °C

2: 93 percent / NaIO₄ / RuCl₃ / acetonitrile; H₂O

3: NaN₃ / acetone; H₂O / 17 h / 25 °C

4: H₂SO₄; H₂O / tetrahydrofuran

With sodium periodate; thionyl chloride; sodium azide; sulfuric acid; water; ruthenium trichloride; In tetrahydrofuran; dichloromethane; water; acetone; acetonitrile;

DOI:10.1016/S0040-4039(01)01338-7

Reference yield:

p-toluenesulfonyl chloride (98-59-9) → C18H21N3O7S2 (231607-41-3)

Guidance literature:

Multi-step reaction with 6 steps

1: 85 percent / NEt₃ / diethyl ether / 17 h / 30 °C

2: 61 percent / aq. HCl / aq. ethanol / 3 h / Heating

3: 96 percent / SOCl₂ / CH₂Cl₂ / 18 h / 20 °C

4: 93 percent / NaIO₄ / RuCl₃ / acetonitrile; H₂O

5: NaN₃ / acetone; H₂O / 17 h / 25 °C

6: H₂SO₄; H₂O / tetrahydrofuran

With hydrogenchloride; sodium periodate; thionyl chloride; sodium azide; sulfuric acid; water; triethylamine; ruthenium trichloride; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane; water; acetone; acetonitrile;

DOI:10.1016/S0040-4039(01)01338-7

Reference yield:

C18H20O9S3 (231607-42-4) → C18H21N3O7S2 (231607-41-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 93 percent / NaIO₄ / RuCl₃ / acetonitrile; H₂O

2: NaN₃ / acetone; H₂O / 17 h / 25 °C

3: H₂SO₄; H₂O / tetrahydrofuran

With sodium periodate; sodium azide; sulfuric acid; water; ruthenium trichloride; In tetrahydrofuran; water; acetone; acetonitrile;

DOI:10.1016/S0040-4039(01)01338-7

upstream raw materials:

(2R,3R)-2,3-dihydroxy-4-{[(4-methylphenyl)sulfonyl]oxy}butyl 4-methyl-1-benzenesulfonate

p-toluenesulfonyl chloride

C₁₈H₂₀O₉S₃

C₁₈H₂₀O₁₀S₃

Downstream raw materials:

Acetic acid 3-{(S)-4-[(S)-1-hydroxy-2-(toluene-4-sulfonyloxy)-ethyl]-4,5-dihydro-oxazol-2-yl}-2-methyl-phenyl ester

Refernces