1-(5-bromopyridin-2-yl)-2-(dimethylamino)ethanol TFA salt

Base Information

• Chemical Name: 1-(5-bromopyridin-2-yl)-2-(dimethylamino)ethanol TFA salt
• CAS No.: 870714-93-5
• Molecular Formula: C₂HF₃O₂*C₉H₁₃BrN₂O
• Molecular Weight: 359.143
• Mol file: 870714-93-5.mol

Synonyms:

Chemical Property of 1-(5-bromopyridin-2-yl)-2-(dimethylamino)ethanol TFA salt

Chemical Property:

Purity/Quality:

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Technology Process of 1-(5-bromopyridin-2-yl)-2-(dimethylamino)ethanol TFA salt

There total 1 articles about 1-(5-bromopyridin-2-yl)-2-(dimethylamino)ethanol TFA salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

2-bromo-1-(5-bromopyridin-2-yl)ethanone hydrobromide (870694-29-4) + dimethyl amine (124-40-3) + triethylamine (121-44-8) → 1-(5-bromopyridin-2-yl)-2-(dimethylamino)ethanol TFA salt (870714-93-5) + dimethylamine TFA salt (2840-17-7) + triethylamine triflouroacetate (454-49-9)

Guidance literature:

2-bromo-1-(5-bromopyridin-2-yl)ethanone hydrobromide; dimethyl amine; triethylamine; In tetrahydrofuran; methanol; at -10 - -5 ℃; for 2h;

With sodium tris(acetoxy)borohydride; In tetrahydrofuran; methanol; at -5 ℃; for 1h;

With hydrogenchloride; potassium hydroxide; trifluoroacetic acid; more than 3 stages;

upstream raw materials:

2-bromo-1-(5-bromopyridin-2-yl)ethanone hydrobromide

dimethyl amine

triethylamine

Refernces