(+)-winterin

Base Information

• Chemical Name: (+)-winterin
• CAS No.: 4795-87-3
• Molecular Formula: C₁₅H₂₀O₃
• Molecular Weight: 248.322
• Mol file: 4795-87-3.mol

Synonyms:

Chemical Property of (+)-winterin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+)-winterin

There total 15 articles about (+)-winterin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

(+/-)-11,14-Dihydroxypodocarpatriene (64597-80-4,144664-33-5) → (+/-)-Winterin (4795-87-3,6754-56-9)

Guidance literature:

With sodium periodate; ruthenium trichloride; In tetrachloromethane; water; acetonitrile; at 25 - 30 ℃; for 15h;

DOI:10.1016/S0040-4020(01)88267-3

Reference yield: 60.0%

(+)-12α-hydroxyisodrimenin (218780-16-6) → (+)-winterin (4795-87-3,6754-56-9)

Guidance literature:

With Jones's reagent; In acetone; Ambient temperature;

DOI:10.1039/a803123a

Reference yield: 55.0%

trans-1,2,3,4,9,10,11,12-Octahydro-8-hydroxy-1,1,12-trimethyl-phenanthren (5750-64-1,106480-13-1,144664-34-6) → (+/-)-Winterin (4795-87-3,6754-56-9)

Guidance literature:

With sodium periodate; ruthenium trichloride; In tetrachloromethane; water; acetonitrile; at 25 - 30 ℃;

DOI:10.1016/S0040-4020(01)88267-3

upstream raw materials:

trans-1,2,3,4,9,10,11,12-Octahydro-8-hydroxy-1,1,12-trimethyl-phenanthren

(+/-)-14-methoxypodocarpa-8,11,13-triene

(4aR,10aR)-5,8-Dimethoxy-1,1,4a-trimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene

(+/-)-11,14-Dihydroxypodocarpatriene

Downstream raw materials:

(+)-isodrimenin

(+)-confertifoline

Refernces

• 1、 Nakano, Tatsuhiko,Villamizar, Jose,Maillo, Maria Aracelis. "Synthesis of Drimanic Sesquiterpenes, (+)-Valdiviolide, (+)-12α-Hydroxyisodrimenin and (+)-Winterin". . p. 560 - 561. Retrieved 2007/10/03.
• 2、 Bendall, Justin G.,Cambie, Richard C.,Grimsdale, Andrew C.,Rutledge, Peter S.,Woodgate, Peul D.. "Synthesis of Winterin from Podocarpic Acid". . p. 1063 - 1067. Retrieved 2007/10/02.