8-5-cyclic dehydrodiferulic acid

Base Information

• Chemical Name: 8-5-cyclic dehydrodiferulic acid
• CAS No.: 353455-91-1
• Molecular Formula: C₂₀H₁₈O₈
• Molecular Weight: 386.358
• Mol file: 353455-91-1.mol

Synonyms:

Chemical Property of 8-5-cyclic dehydrodiferulic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 8-5-cyclic dehydrodiferulic acid

There total 4 articles about 8-5-cyclic dehydrodiferulic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 11.19%

3-(4-hydroxy-3-methoxyphenyl)acrylic acid (1135-24-6,537-98-4) → 8-5-cyclic dehydrodiferulic acid (353455-91-1) + 3,6-bis-(4-hydroxy-3-methoxy-phenyl)-tetrahydro-furo[3,4-c]furan-1,4-dione (63358-16-7,77550-11-9,66701-55-1,13962-76-0)

Guidance literature:

With laccase; In ethyl acetate; at 28 ℃; for 24h; pH=5; aq. acetate buffer; Enzymatic reaction;

DOI:10.1016/j.molcatb.2011.08.010

Reference yield:

3-(4-hydroxy-3-methoxyphenyl)acrylic acid (1135-24-6,537-98-4) → 8-5-cyclic dehydrodiferulic acid (353455-91-1)

Guidance literature:

With laccase from myceliophthora thermophila sp.; In methanol; aq. phosphate buffer; at 30 ℃; Kinetics; Green chemistry; Enzymatic reaction;

DOI:10.1016/j.foodchem.2013.07.119

Reference yield:

ethyl ferulate (28028-62-8,74257-26-4,4046-02-0) → 8-5-cyclic dehydrodiferulic acid (353455-91-1) + 5,8’-dehydrodiferulic acid

Guidance literature:

Multi-step reaction with 2 steps

1: dihydrogen peroxide; peroxidase / Enzymatic reaction

2: sodium hydroxide / 12 h / Darkness

With dihydrogen peroxide; sodium hydroxide; peroxidase;

DOI:10.1021/acs.jafc.5b03234

upstream raw materials:

3-(4-hydroxy-3-methoxyphenyl)acrylic acid

ethyl ferulate

diethyl ester of 8-5-cyclic dehydrodiferulic acid

Refernces

• 1、 Schendel, Rachel R.,Karrer, Cecile,Bunzel, Diana,Huch, Melanie,Hildebrand, Andreas A.,Kulling, Sabine E.,Bunzel, Mirko. "Structural Transformation of 8-5-Coupled Dehydrodiferulates by Human Intestinal Microbiota". . p. 7975 - 7985. Retrieved 2015.