Technology Process of C14H14ClNO3
There total 5 articles about C14H14ClNO3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
boron tribromide;
In
dichloromethane;
at -78 ℃;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: potassium carbonate / acetone / Reflux
2: (3aR)-1-methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole; dimethylsulfide borane complex / tetrahydrofuran / -10 °C
3: sodium azide / N,N-dimethyl-formamide / 20 °C
4: copper(l) iodide; sodium hydroxide / dimethyl sulfoxide; water / 90 °C
5: boron tribromide / dichloromethane / -78 °C
With
copper(l) iodide; sodium azide; dimethylsulfide borane complex; boron tribromide; potassium carbonate; sodium hydroxide; (3aR)-1-methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole;
In
tetrahydrofuran; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide; acetone;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: (3aR)-1-methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole; dimethylsulfide borane complex / tetrahydrofuran / -10 °C
2: sodium azide / N,N-dimethyl-formamide / 20 °C
3: copper(l) iodide; sodium hydroxide / dimethyl sulfoxide; water / 90 °C
4: boron tribromide / dichloromethane / -78 °C
With
copper(l) iodide; sodium azide; dimethylsulfide borane complex; boron tribromide; sodium hydroxide; (3aR)-1-methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole;
In
tetrahydrofuran; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide;
