Benzoyl chloride, 3-butoxy-4-methoxy-

Base Information

• Chemical Name: Benzoyl chloride, 3-butoxy-4-methoxy-
• CAS No.: 139488-45-2
• Molecular Formula: C12H15ClO3
• Molecular Weight: 242.702
• Mol file: 139488-45-2.mol

Synonyms:

Chemical Property of Benzoyl chloride, 3-butoxy-4-methoxy-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzoyl chloride, 3-butoxy-4-methoxy-

There total 4 articles about Benzoyl chloride, 3-butoxy-4-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

acide 3-n-butoxy-4-methoxybenzoique (66924-20-7) → 3-(n-butoxy)-4-methoxybenzoyl chloride (139488-45-2)

Guidance literature:

With thionyl chloride; 1.) reflux, 2 h, 2.) RT, 1.5 h;

DOI:10.1080/00397919208021073

Reference yield:

isovanillin (621-59-0) → 3-(n-butoxy)-4-methoxybenzoyl chloride (139488-45-2)

Guidance literature:

Multi-step reaction with 3 steps

1: K₂CO₃, KI / dimethylformamide / 21 h / 65 °C

2: sulfamic acid, aq. AcOH, aq. NaClO₂ / 1 h / Ambient temperature

3: SOCl₂ / toluene; dimethylformamide / 5 h / Heating

With sodium chlorite; thionyl chloride; aminosulfonic acid; potassium carbonate; acetic acid; potassium iodide; In N,N-dimethyl-formamide; toluene;

DOI:10.1021/jm00037a021

Reference yield:

3-butyloxy-4-methoxybenzaldehyde (34127-96-3) → 3-(n-butoxy)-4-methoxybenzoyl chloride (139488-45-2)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfamic acid, aq. AcOH, aq. NaClO₂ / 1 h / Ambient temperature

2: SOCl₂ / toluene; dimethylformamide / 5 h / Heating

With sodium chlorite; thionyl chloride; aminosulfonic acid; acetic acid; In N,N-dimethyl-formamide; toluene;

DOI:10.1021/jm00037a021

upstream raw materials:

acide 3-n-butoxy-4-methoxybenzoique

isovanillin

3-butyloxy-4-methoxybenzaldehyde

methyl 3-(n-butoxy)-4-methoxybenzoate

Downstream raw materials:

5-<3-(n-butoxy)-4-methoxyphenyl>-3-methyl-2-methylimino-1,3,4-oxadiazole

1-<3-(n-butoxy)-4-methoxybenzoyl>-2,4-dimethylthiosemicarbazide

Refernces

• 1、 Kane,Staeger. "An improved method for the synthesis of 5-aryl-3-methyl-2-methylimino-1,3,4-oxadiazoles". . p. 1 - 11. Retrieved 2007/10/02.