C₂₄H₃₃NO

Base Information

• Chemical Name: C₂₄H₃₃NO
• CAS No.: 1382475-29-7
• Molecular Formula: C₂₄H₃₃NO
• Molecular Weight: 351.532
• Mol file: 1382475-29-7.mol

Synonyms:

Chemical Property of C₂₄H₃₃NO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₃₃NO

There total 3 articles about C₂₄H₃₃NO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

C19H29IO (32138-70-8) + 3-pyridylboronic acid (1692-25-7) → C24H33NO (1382475-29-7,1940176-03-3)

Guidance literature:

C₁₉H₂₉IO; 3-pyridylboronic acid; With potassium carbonate; In 1,4-dioxane; water; at 20 ℃; for 0.25h;

tetrakis(triphenylphosphine) palladium⁽⁰⁾; at 80 ℃; for 0.5h;

Reference yield:

3β-hydroxyandrostan-17-one (20120-08-5) → C24H33NO (1382475-29-7,1940176-03-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: hydrazine hydrate; triethylamine / ethanol / 2 h / Reflux

2.1: iodine; triethylamine / tetrahydrofuran; dichloromethane / 2 h / 0 - 20 °C

3.1: potassium carbonate / 1,4-dioxane; water / 0.25 h / 20 °C

3.2: 0.5 h / 80 °C

With iodine; potassium carbonate; hydrazine hydrate; triethylamine; In tetrahydrofuran; 1,4-dioxane; ethanol; dichloromethane; water; 3.1: Suzuki Coupling / 3.2: Suzuki Coupling;

Reference yield:

C19H32N2O (1382475-26-4) → C24H33NO (1382475-29-7,1940176-03-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: iodine; triethylamine / tetrahydrofuran; dichloromethane / 2 h / 0 - 20 °C

2.1: potassium carbonate / 1,4-dioxane; water / 0.25 h / 20 °C

2.2: 0.5 h / 80 °C

With iodine; potassium carbonate; triethylamine; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water; 2.1: Suzuki Coupling / 2.2: Suzuki Coupling;

upstream raw materials:

C₁₉H₂₉IO

3-pyridylboronic acid

3β-hydroxyandrostan-17-one

C₁₉H₃₂N₂O

Downstream raw materials:

17-(pyridin-3-yl)androst-16-en-3-one

Refernces