C₂₈H₃₇BF₂N₄

Base Information

• Chemical Name: C₂₈H₃₇BF₂N₄
• CAS No.: 1617500-14-7
• Molecular Formula: C₂₈H₃₇BF₂N₄
• Molecular Weight: 478.436
• Mol file: 1617500-14-7.mol

Synonyms:

Chemical Property of C₂₈H₃₇BF₂N₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₈H₃₇BF₂N₄

There total 5 articles about C₂₈H₃₇BF₂N₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4-dimethyl-3-ethyl-pyrrole (517-22-6) → C28H37BF2N4 (1617500-14-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: trifluoroacetic acid / dichloromethane / 18 h / 20 °C / Inert atmosphere

1.2: 1 h / 20 °C / Inert atmosphere

2.1: N-ethyl-N,N-diisopropylamine / toluene / 0.17 h / 20 °C / Inert atmosphere

2.2: 1 h / Inert atmosphere

3.1: hydrazine hydrate; palladium 10% on activated carbon / ethanol; tetrahydrofuran / 0.5 h / Inert atmosphere; Reflux

With palladium 10% on activated carbon; hydrazine hydrate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In tetrahydrofuran; ethanol; dichloromethane; toluene;

DOI:10.1021/ja5010174

Reference yield:

C28H36N4O2 → C28H37BF2N4 (1617500-14-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: N-ethyl-N,N-diisopropylamine / toluene / 0.17 h / 20 °C / Inert atmosphere

1.2: 1 h / Inert atmosphere

2.1: hydrazine hydrate; palladium 10% on activated carbon / ethanol; tetrahydrofuran / 0.5 h / Inert atmosphere; Reflux

With palladium 10% on activated carbon; hydrazine hydrate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; ethanol; toluene;

DOI:10.1021/ja5010174

Reference yield:

5-nitro-2-(piperidin-1-yl)benzaldehyde (30742-60-0) → C28H37BF2N4 (1617500-14-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: trifluoroacetic acid / dichloromethane / 18 h / 20 °C / Inert atmosphere

1.2: 1 h / 20 °C / Inert atmosphere

2.1: N-ethyl-N,N-diisopropylamine / toluene / 0.17 h / 20 °C / Inert atmosphere

2.2: 1 h / Inert atmosphere

3.1: hydrazine hydrate; palladium 10% on activated carbon / ethanol; tetrahydrofuran / 0.5 h / Inert atmosphere; Reflux

With palladium 10% on activated carbon; hydrazine hydrate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In tetrahydrofuran; ethanol; dichloromethane; toluene;

DOI:10.1021/ja5010174

upstream raw materials:

2,4-dimethyl-3-ethyl-pyrrole

5-nitro-2-(piperidin-1-yl)benzaldehyde

2,6-diethyl-4,4-difluoro-8-(2-piperidino-5-nitrophenyl)-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene

Downstream raw materials:

8-(5-azido-2-piperidinophenyl)-2,6-diethyl-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene

Refernces

• 1、 Shie, Jiun-Jie,Liu, Ying-Chih,Lee, Yu-Ming,Lim, Carmay,Fang, Jim-Min,Wong, Chi-Huey. "An azido-BODIPY probe for glycosylation: Initiation of strong fluorescence upon triazole formation". . p. 9953 - 9961. Retrieved 2014/08/05.