C₄₆H₅₈N₅O₁₄PSi*H₃N

Base Information

• Chemical Name: C₄₆H₅₈N₅O₁₄PSi*H₃N
• CAS No.: 118362-05-3
• Molecular Formula: C₄₆H₅₈N₅O₁₄PSi*H₃N
• Molecular Weight: 981.081
• Mol file: 118362-05-3.mol

Synonyms:

Chemical Property of C₄₆H₅₈N₅O₁₄PSi*H₃N

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of C₄₆H₅₈N₅O₁₄PSi*H₃N

There total 2 articles about C₄₆H₅₈N₅O₁₄PSi*H₃N which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5’-O-(1,1-bis(4-methoxyphenyl)-1-phenylmethyl)-2’-O-tert-butyldimethylsilylcytidine (129666-74-6,81256-87-3) → C46H58N5O14PSi*H3N (118362-05-3)

Guidance literature:

Multi-step reaction with 2 steps

1: diisopropylammonium tetrazolide / acetonitrile / 15 h

2: 2.) conc. aq. NH₃ / 1.) CH₃CN, 2.) 50 deg C, 16 h

With ammonium hydroxide; N,N-diisopropylamine tetrazolide; In acetonitrile;

Reference yield:

N4-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)cytidine 3'-O-(2-cyanoethyl N,N-diisopropylphosphoramidite) (118380-84-0,131349-30-9,131349-36-5) → C46H58N5O14PSi*H3N (118362-05-3)

Guidance literature:

With ammonium hydroxide; Multistep reaction; 1.) CH₃CN, 2.) 50 deg C, 16 h;

upstream raw materials:

N⁴-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)cytidine 3'-O-(2-cyanoethyl N,N-diisopropylphosphoramidite)

5’-O-(1,1-bis(4-methoxyphenyl)-1-phenylmethyl)-2’-O-tert-butyldimethylsilylcytidine

Refernces