2-(Diethoxymethyl)thiophene

Base Information

• Chemical Name: 2-(Diethoxymethyl)thiophene
• CAS No.: 13959-97-2
• Molecular Formula: C9H14O2S
• Molecular Weight: 186.275
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID30483948
• Wikidata: Q72508823
• Mol file: 13959-97-2.mol

Synonyms:2-(diethoxymethyl)thiophene;13959-97-2;Thiophene-2-carboxaldehyde diethylacetal;2-Diethoxymethylthiophene;2-diethoxy methyl thiophene;2-(diethoxymethyl) thiophene;2-(diethoxymethyl)-thiophene;2-(diethoxy-methyl)-thiophene;SCHEMBL8409514;Thiophene, 2-(diethoxymethyl)-;DTXSID30483948;XAGPTGMAMGKKTF-UHFFFAOYSA-N;MFCD11109382;AKOS006306121;2-thiophenecarboxaldehyde diethyl acetal;CS-0445686;FT-0722324;J-506352

Chemical Property of 2-(Diethoxymethyl)thiophene

Chemical Property:

• Vapor Pressure: 0.176mmHg at 25°C
• Boiling Point: 219.432oC at 760 mmHg
• Flash Point: 86.51oC
• PSA: 46.70000
• Density: 1.066g/cm3
• LogP: 2.81970
• Storage Temp.: 2-8°C
• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 186.07145086
• Heavy Atom Count: 12
• Complexity: 113

Purity/Quality:

98% ^*data from raw suppliers

2-(Diethoxymethyl)thiophene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(C1=CC=CS1)OCC

Technology Process of 2-(Diethoxymethyl)thiophene

There total 5 articles about 2-(Diethoxymethyl)thiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

thiophene-2-carbaldehyde (98-03-3) + orthoformic acid triethyl ester (122-51-0) → 2-thiophenealdehyde diethyl acetal (13959-97-2)

Guidance literature:

With ammonium chloride; In ethanol; for 16h; Heating;

DOI:10.1016/j.tet.2005.03.016

Reference yield: 89.0%

thiophene-2-carbaldehyde (98-03-3) + ethanol (64-17-5) → 2-thiophenealdehyde diethyl acetal (13959-97-2)

Guidance literature:

With aromatic sulfonated UiO-66 metal-organic framework; at 23 ℃; for 2h;

DOI:10.1039/c6ra14365b

Reference yield:

thiophene-2-carbaldehyde (98-03-3) + NH4 NO3 + (EtO)3 CH + sodium carbonate (497-19-8) → 2-thiophenealdehyde diethyl acetal (13959-97-2)

Guidance literature:

upstream raw materials:

2-Iodothiophene

orthoformic acid triethyl ester

thiophene-2-carbaldehyde

sodium carbonate

Downstream raw materials:

2-ethoxycarbonyl-thiophene-5-carboxaldehyde

valeraldehyde-(2,4-dinitro-phenylhydrazone)

3,4-bis[5-(diethoxymethyl)thien-2-yl]-2,5-dihydro-1-benzyl-1H-pyrrole-2,5-dione

C₂₁H₂₂N₄O₂S₃

Refernces

• 1、 Miao, Zongcheng,Qi, Chao,Wensley, Allison M.,Luan, Yi. "Development of a novel Br?nsted acid UiO-66 metal-organic framework catalyst by postsynthetic modification and its application in catalysis". . p. 67226 - 67231. Retrieved 2016/07/30.
• 2、 -. "Naphthenic and heterocyclic retinoic acid analogues". . . Retrieved 2008/06/13.