3-<<<2-<(diaminomethylene)amino>-5-(benzylideneamino)-4-thiazolyl>methyl>thio>propionitrile hydrochloride

Base Information

• Chemical Name: 3-<<<2-<(diaminomethylene)amino>-5-(benzylideneamino)-4-thiazolyl>methyl>thio>propionitrile hydrochloride
• CAS No.: 109467-14-3
• Molecular Formula: C₁₅H₁₆N₆S₂*ClH
• Molecular Weight: 380.925
• Mol file: 109467-14-3.mol

Synonyms:

Chemical Property of 3-<<<2-<(diaminomethylene)amino>-5-(benzylideneamino)-4-thiazolyl>methyl>thio>propionitrile hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-<<<2-<(diaminomethylene)amino>-5-(benzylideneamino)-4-thiazolyl>methyl>thio>propionitrile hydrochloride

There total 2 articles about 3-<<<2-<(diaminomethylene)amino>-5-(benzylideneamino)-4-thiazolyl>methyl>thio>propionitrile hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N''-[4-[[(2-cyanoethyl)thio]methyl]-2-thiazolyl]-guanidine (76823-93-3) → 3-<<<2-<(diaminomethylene)amino>-5-(benzylideneamino)-4-thiazolyl>methyl>thio>propionitrile hydrochloride (109467-14-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 71.4 percent / 1 N HCl, NaNO₂ / 1 h / Ambient temperature

2: 1.) H₂ / 1.) 10percent Pd/C / 1.) MeOH, , 2.) MeOH, RT, 48 h

With hydrogenchloride; hydrogen; sodium nitrite; palladium on activated charcoal;

DOI:10.1021/jm00393a018

Reference yield:

benzaldehyde (100-52-7) + 3-<<<2-<(diaminomethylene)amino>-4-hydroxy-5-(hydroxyimino)thiazolin-4yl>methyl>thio>propionitrile hydrochloride (109467-10-9) → 3-<<<2-<(diaminomethylene)amino>-5-(benzylideneamino)-4-thiazolyl>methyl>thio>propionitrile hydrochloride (109467-14-3)

Guidance literature:

With hydrogen; palladium on activated charcoal; Yield given. Multistep reaction; 1.) MeOH, , 2.) MeOH, RT, 48 h;

DOI:10.1021/jm00393a018

upstream raw materials:

benzaldehyde

3-<<<2-<(diaminomethylene)amino>-4-hydroxy-5-(hydroxyimino)thiazolin-4yl>methyl>thio>propionitrile hydrochloride

N''-[4-[[(2-cyanoethyl)thio]methyl]-2-thiazolyl]-guanidine

Refernces