dimethyl-dithiocarbamic acid 4-methyl-5-phenylcarbamoyl-thiazol-2-yl ester

Base Information

• Chemical Name: dimethyl-dithiocarbamic acid 4-methyl-5-phenylcarbamoyl-thiazol-2-yl ester
• CAS No.: 40003-31-4
• Molecular Formula: C₁₄H₁₅N₃OS₃
• Molecular Weight: 337.491
• Mol file: 40003-31-4.mol

Synonyms:

Chemical Property of dimethyl-dithiocarbamic acid 4-methyl-5-phenylcarbamoyl-thiazol-2-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of dimethyl-dithiocarbamic acid 4-methyl-5-phenylcarbamoyl-thiazol-2-yl ester

There total 3 articles about dimethyl-dithiocarbamic acid 4-methyl-5-phenylcarbamoyl-thiazol-2-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-4-methyl-thiazole-5-carboxylic acid (40003-41-6) → dimethyl-dithiocarbamic acid 4-methyl-5-phenylcarbamoyl-thiazol-2-yl ester (40003-31-4)

Guidance literature:

Multi-step reaction with 2 steps

1: POCl₃

2: acetone; H₂O

With trichlorophosphate; In water; acetone;

Reference yield:

ethyl-2-amino-4-methylthiazole-5-carboxylate (7210-76-6) → dimethyl-dithiocarbamic acid 4-methyl-5-phenylcarbamoyl-thiazol-2-yl ester (40003-31-4)

Guidance literature:

Multi-step reaction with 4 steps

1: (i) aq. HBr, NaNO₂, (ii) CuBr

2: NaOH / methanol

3: POCl₃

4: acetone; H₂O

With sodium hydroxide; trichlorophosphate; In methanol; water; acetone;

Reference yield:

sodium dimethyldithiocarbamate (128-04-1) + 2-bromo-4-methyl-N-phenylthiazole-5-carboxamide (40003-45-0) → dimethyl-dithiocarbamic acid 4-methyl-5-phenylcarbamoyl-thiazol-2-yl ester (40003-31-4)

Guidance literature:

In water; acetone;

upstream raw materials:

sodium dimethyldithiocarbamate

2-bromo-4-methyl-N-phenylthiazole-5-carboxamide

2-bromo-4-methyl-thiazole-5-carboxylic acid

ethyl-2-amino-4-methylthiazole-5-carboxylate