rac-phenylalaninol

Base Information

• Chemical Name: rac-phenylalaninol
• CAS No.: 1795-98-8
• Molecular Formula: C₉H₁₃NO
• Molecular Weight: 151.208
• Mol file: 1795-98-8.mol

Synonyms:

Chemical Property of rac-phenylalaninol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of rac-phenylalaninol

There total 24 articles about rac-phenylalaninol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Phenylalanine (150-30-1,25191-15-5,658-69-5,67675-33-6) → rac-phenylalaninol (1795-98-8,3182-95-4,5267-64-1,16088-07-6)

Guidance literature:

With sodium tetrahydroborate; iodine;

DOI:10.1002/cctc.202000597

Reference yield: 80.0%

ethyl 2-(hydroxyimino)-3-phenylpropanoate (6943-96-0,70564-52-2,70564-53-3) → rac-phenylalaninol (1795-98-8,3182-95-4,5267-64-1,16088-07-6)

Guidance literature:

With sodium tetrahydroborate; iodine; In tetrahydrofuran; for 4h; Heating;

DOI:10.1055/s-2003-41046

Reference yield: 77.0%

Phenylalanine (150-30-1,25191-15-5,658-69-5,67675-33-6) + dimethyl sulfide borane (13292-87-0) → rac-phenylalaninol (1795-98-8,3182-95-4,5267-64-1,16088-07-6)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; water;

upstream raw materials:

ethyl N-acetyl-DL-phenylalaninate

Z-β-ethoxycarbonyl-β-nitrostyrene

phenylalanine ethyl ester

acetic acid-(β-nitro-cinnamyl ester)

Downstream raw materials:

2-[5-benzyloxycarbonylamino-2-(4-fluorophenyl)-6-oxo-1,6-dihydro-1-pyrimidinyl]-N-[1-hydroxymethyl-2-phenylethyl]acetamide

L-Phenylalaninol

(R)-2-amino-3-phenylpropanol

1-bromomethyl-2-phenyl-ethylamine; hydrobromide

Refernces

• 1、 Tian, Yingying,Kunz, Doris. "Nucleophilic RhI Catalyzed Selective Isomerization of Terminal Aziridines to Enamides". . p. 4272 - 4275. Retrieved 2020/07/04.
• 2、 -. "Ligand, metal complex containing ligand, and reaction using metal complex containing ligand". Page/Page column 46-50. . Retrieved 2016/10/31.