Acetophenone, 2'-(2-(dimethylamino)ethoxy)-

Base Information

• Chemical Name: Acetophenone, 2'-(2-(dimethylamino)ethoxy)-
• CAS No.: 2089-20-5
• Molecular Formula: C12H17 N O2
• Molecular Weight: 207.272
• Hs Code.: 2922509090
• DSSTox Substance ID: DTXSID90175034
• Wikidata: Q83045260
• Mol file: 2089-20-5.mol

Synonyms:2089-20-5;ACETOPHENONE, 2'-(2-(DIMETHYLAMINO)ETHOXY)-;1-[2-[2-(dimethylamino)ethoxy]phenyl]ethanone;BRN 1961686;2'-(2-(Dimethylamino)ethoxy)acetophenone;1-(2-(2-dimethylaminoethoxy)phenyl)ethanone;1-[2-(2-DIMETHYLAMINOETHOXY)PHENYL]ETHANONE;SCHEMBL6669660;DTXSID90175034;PKEROHUSQKVCKS-UHFFFAOYSA-N;AKOS000173987;1-[2-(2-dimethylamino-ethoxy)-phenyl]-ethanone;4-08-00-00322 (Beilstein Handbook Reference)

Chemical Property of Acetophenone, 2'-(2-(dimethylamino)ethoxy)-

Chemical Property:

• Vapor Pressure: 0.000897mmHg at 25°C
• Boiling Point: 304°Cat760mmHg
• Flash Point: 137.7°C
• PSA: 29.54000
• Density: 1.027g/cm³
• LogP: 1.82960
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 207.125928785
• Heavy Atom Count: 15
• Complexity: 204

Purity/Quality:

2'-(2-(DIMETHYLAMINO)ETHOXY)ACETOPHENONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)C1=CC=CC=C1OCCN(C)C

Technology Process of Acetophenone, 2'-(2-(dimethylamino)ethoxy)-

There total 3 articles about Acetophenone, 2'-(2-(dimethylamino)ethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

(2-chloroethyl)dimethylamine hydrochloride (4584-46-7) + o-hydroxyacetophenone (118-93-4,104809-67-8) → 1-[2-(2-dimethylamino-ethoxy)-phenyl]-ethanone (2089-20-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 48h;

DOI:10.1080/10610278.2010.491153

Reference yield:

2-(dimethylamino)ethyl chloride (107-99-3) → 1-[2-(2-dimethylamino-ethoxy)-phenyl]-ethanone (2089-20-5)

Guidance literature:

With benzene;

Reference yield:

→ 1-[2-(2-dimethylamino-ethoxy)-phenyl]-ethanone (2089-20-5)

Guidance literature:

Entspr. Phenoxyalkylbromid, ethan. Me2NH;

upstream raw materials:

2-(dimethylamino)ethyl chloride

(2-chloroethyl)dimethylamine hydrochloride

o-hydroxyacetophenone

Downstream raw materials:

C₁₈H₁₉N₃O

5-{2-[2-(N,N-Dimethylamino)ethyl]oxy-phenyl}-3-phenyl-1,2,4-triazine

[2-(2-dimethylamino-ethoxy)-phenyl]-oxo-acetaldehyde

Refernces

• 1、 -. "NOVEL DIPHENYL-SUBSTITUTED 6-RING-HETEROCYCLES, METHODS FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS". Page 7. . Retrieved 2010/02/08.