(R)-(+)-(1-trifluoromethyl)octanol

Base Information

• Chemical Name: (R)-(+)-(1-trifluoromethyl)octanol
• CAS No.: 175655-85-3
• Molecular Formula: C₉H₁₇F₃O
• Molecular Weight: 198.229
• Mol file: 175655-85-3.mol

Synonyms:

Chemical Property of (R)-(+)-(1-trifluoromethyl)octanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-(+)-(1-trifluoromethyl)octanol

There total 1 articles about (R)-(+)-(1-trifluoromethyl)octanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,1,1-trifluorononan-2-one (26902-66-9) → (R)-(+)-(1-trifluoromethyl)octanol (175655-85-3) + (S)-(-)-(1-trifluoromethyl)octanol (147991-84-2)

Guidance literature:

With (-)-diisopinocamphenylborane chloride; for 8h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;

DOI:10.1016/S0040-4020(01)80530-5

Reference yield:

(R)-(+)-(1-trifluoromethyl)octanol (175655-85-3) → (S)-(-)-4-<(1-trifluoromethyloctyloxycarbonyl)phenyl> 4'-hexyloxybiphenyl-4-carboxylate

Guidance literature:

Multi-step reaction with 2 steps

1: p-toluenesulfonic acid / xylene / 15 h / Heating

2: pyridine / CH₂Cl₂ / 72 h / Ambient temperature

With pyridine; toluene-4-sulfonic acid; In dichloromethane; xylene;

DOI:10.1016/S0022-1139(00)80027-5

Reference yield:

(R)-(+)-(1-trifluoromethyl)octanol (175655-85-3) → (R)-(+)-4-<(1-trifluoromethyloctyloxycarbonyl)phenyl> 4'-hexyloxybiphenyl-4-carboxylate

Guidance literature:

Multi-step reaction with 2 steps

1: p-toluenesulfonic acid / xylene / 15 h / Heating

2: pyridine / CH₂Cl₂ / 72 h / Ambient temperature

With pyridine; toluene-4-sulfonic acid; In dichloromethane; xylene;

DOI:10.1016/S0022-1139(00)80027-5

upstream raw materials:

1,1,1-trifluorononan-2-one

Downstream raw materials:

(S)-(-)-1-(trifluoromethyl)octyl p-hydroxybenzoate

(R)-(+)-1-(trifluoromethyl)octyl p-hydroxybenzoate

Refernces