(⁽¹⁵⁾N)tritylglycine

Base Information

• Chemical Name: (⁽¹⁵⁾N)tritylglycine
• CAS No.: 186973-01-3
• Molecular Formula: C₂₁H₁₉NO₂
• Molecular Weight: 318.381
• Mol file: 186973-01-3.mol

Synonyms:

Chemical Property of (⁽¹⁵⁾N)tritylglycine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (⁽¹⁵⁾N)tritylglycine

There total 1 articles about (⁽¹⁵⁾N)tritylglycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.6%

glycine-15N (7299-33-4) + trityl chloride (76-83-5) → ((15)N)tritylglycine (186973-01-3)

Guidance literature:

In water; isopropyl alcohol; for 5h; Ambient temperature;

DOI:10.1055/s-1997-1208

Reference yield:

((15)N)tritylglycine (186973-01-3) → ((15)N2)tritylglycinamide (190787-45-2)

Guidance literature:

With ammonia; chloroformic acid ethyl ester; triethylamine; Yield given. Multistep reaction; 1.) CHCl₃, 0 deg C, 30 min, 2.) CHCl₃, a) -70 deg C, 20 min, b) RT, 1 h;

DOI:10.1055/s-1997-1208

Reference yield:

((15)N)tritylglycine (186973-01-3) + ((15)N2)monotritylethylenediamine (186972-97-4) → 1-[((15)N)tritylglycyl]-2-[((15)N2)monotrityl]ethylenediamine

Guidance literature:

With chloroformic acid ethyl ester; triethylamine; Yield given. Multistep reaction; 1.) CHCl₃, 20 min, 2.) CHCl₃, RT, 3 h;

DOI:10.1055/s-1997-1208

upstream raw materials:

glycine-15N

trityl chloride

Downstream raw materials:

(⁽¹⁵⁾N₂)tritylglycinamide

Refernces

• 1、 Zang, Erle,Sadler, Peter J.. "A convenient synthesis of 15N-labeled diethylenetriamine [(15N)dien] and ethylenediamine [(15N)En]". . p. 410 - 412. Retrieved 2007/10/03.