4-fluoro-isophthalic acid bis-(3-dipropylamino-propylester); dihydrochloride

Base Information

• Chemical Name: 4-fluoro-isophthalic acid bis-(3-dipropylamino-propylester); dihydrochloride
• CAS No.: 453-68-9
• Molecular Formula: C₂₆H₄₃FN₂O₄*2ClH
• Molecular Weight: 539.559
• Mol file: 453-68-9.mol

Synonyms:

Chemical Property of 4-fluoro-isophthalic acid bis-(3-dipropylamino-propylester); dihydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-fluoro-isophthalic acid bis-(3-dipropylamino-propylester); dihydrochloride

There total 3 articles about 4-fluoro-isophthalic acid bis-(3-dipropylamino-propylester); dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-fluorobenzene-1,3-dioic acid (327-95-7) → 4-fluoro-isophthalic acid bis-(3-dipropylamino-propylester); dihydrochloride (453-68-9)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride

2: benzene

With thionyl chloride; benzene;

DOI:10.1021/ja01252a016

Reference yield:

2,4-dimethylfluorobenzene (452-65-3) → 4-fluoro-isophthalic acid bis-(3-dipropylamino-propylester); dihydrochloride (453-68-9)

Guidance literature:

Multi-step reaction with 3 steps

1: aqueous potassium permanganate

2: thionyl chloride

3: benzene

With potassium permanganate; thionyl chloride; benzene;

DOI:10.1021/ja01252a016

Reference yield:

3-(N,N-dipropylamino)propan-1-ol (34003-67-3) + 4-fluoro-isophthaloyl chloride (327-94-6) → 4-fluoro-isophthalic acid bis-(3-dipropylamino-propylester); dihydrochloride (453-68-9)

Guidance literature:

With benzene;

DOI:10.1021/ja01252a016

upstream raw materials:

3-(N,N-dipropylamino)propan-1-ol

4-fluoro-isophthaloyl chloride

4-fluorobenzene-1,3-dioic acid

2,4-dimethylfluorobenzene