Procysbi

Base Information Edit

Chemical Name:Procysbi
CAS No.:27761-19-9
Molecular Formula:C6H13NO6S
Molecular Weight:227.238
Hs Code.:2930909090
European Community (EC) Number:248-641-7
UNII:QO84GZ3TST
DSSTox Substance ID:DTXSID801026168
NCI Thesaurus Code:C47467
RXCUI:81990
Mol file:27761-19-9.mol

Synonyms:Procysbi;27761-19-9;QO84GZ3TST;Mercaptamine bitartrate;Ethanethiol, 2-amino-, (2R,3R)-2,3-dihydroxybutanedioate (1:1);UNII-QO84GZ3TST;Cysteamine bitartrate (JAN);2-aminoethanethiol;(2R,3R)-2,3-dihydroxybutanedioic acid;beta-Mercaptoethylamine bitartrate;RP103;CYSTEAMINE BITARTRATE [JAN];beta-Mercaptoethylamine hydrogen tartrate;Ethanethiol, 2-amino-, tartrate (1:1) (salt);RP-103;Cystagon (TN);Procysbi (TN);CYSTEAMINEBITARTRATE;CYSTEAMINE BITARTRATE [MI];DTXSID801026168;CYSTEAMINE BITARTRATE [VANDF];MERCAPTAMINE BITARTRATE [MART.];MERCAPTAMINE BITARTRATE [WHO-DD];CYSTEAMINE BITARTRATE [ORANGE BOOK];D10468;E83656;.BETA.-MERCAPTOETHYLAMINE HYDROGEN TARTRATE;2-Aminoethanethiol (2R,3R)-2,3-dihydroxysuccinate

Suppliers and Price of Procysbi

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
Cysteaminebitartrate >98%
250 mg
$ 450.00

DC Chemicals
Cysteaminebitartrate >98%
100 mg
$ 300.00

DC Chemicals
Cysteaminebitartrate >98%
1 g
$ 800.00

American Custom Chemicals Corporation
CYSTEAMINE BITARTRATE 95.00%
5MG
$ 503.66

Total 47 raw suppliers

Chemical Property of Procysbi Edit

Chemical Property:

Vapor Pressure:4.93E-08mmHg at 25°C
Melting Point:97-98.5oC
Boiling Point:133.6°Cat760mmHg
Flash Point:34.6°C
PSA：182.71000
Density:0.973g/cm³
LogP:-2.53610
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:227.04635831
Heavy Atom Count:14
Complexity:144

Purity/Quality:

99%, ^*data from raw suppliers

Cysteaminebitartrate >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(CS)N.C(C(C(=O)O)O)(C(=O)O)O
Isomeric SMILES:C(CS)N.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O
Recent ClinicalTrials:Open-Label, Safety and Superior Effectiveness Study of Cysteamine Bitartrate Delayed-Release Capsules (RP103) in Cystinosis
Recent EU Clinical Trials:A PHASE 1B/2A STUDY TO ASSESS THE TOLERABILITY AND ADVERSE EFFECT PROFILE OF CYSTEAMINE (CYSTAGON) IN ADULTS AND CHILDREN WITH HOMOZYGOUS ΔF508 CYSTIC FIBROSIS, IN PATIENTS TAKING EPIGALLOCATECHIN-3-GALLATE (EGCG, EPINERVE) FOOD SUPPLEMENTATION
Uses Cysteamine bitartrate (CAS# 27761-19-9) treatment of cystinosis and other metabolic and neurodegenerative diseases.

Technology Process of Procysbi

There total 2 articles about Procysbi which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 87-69-4,138508-61-9
L-Tartaric acid

: 2-mercaptoethylamine hydrochloride

: 27761-19-9
cysteamine bitartrate

Guidance literature:: 2-mercaptoethylamine hydrochloride; With 3-tert-butyl-4-methoxyphenol; sodium hydroxide; In ethanol; at 5 - 15 ℃; for 1.25h;

L-Tartaric acid; With 3-tert-butyl-4-methoxyphenol; In ethanol; at 55 - 75 ℃; for 0.75h;