Technology Process of 1H-Purine-2,6-dione,
3,7-dihydro-3-[(4-hydroxy-3-nitrophenyl)methyl]-1,7-dimethyl-
There total 7 articles about 1H-Purine-2,6-dione,
3,7-dihydro-3-[(4-hydroxy-3-nitrophenyl)methyl]-1,7-dimethyl- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sulfuric acid;
In
acetic acid;
for 1h;
Heating;
DOI:10.1248/cpb.39.2855
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) K2CO3 / 1.) DMF, 80 deg C, 1 h, 2.) room temperature, 3 h
2: 70 percent / H2, 70percent aq. HClO4 / 10percent Pd/C / acetic acid / 760 Torr / 1.) 40 deg C, 4 h, 2.) 60 deg C, 13 h
3: 1.) K2CO3 / 1.) DMF, 88 deg C, 1 h, 2.) room temperature, 3 h
4: 81 percent / 2 N aq. H2SO4 / acetic acid / 1 h / Heating
With
perchloric acid; sulfuric acid; hydrogen; potassium carbonate;
palladium on activated charcoal;
In
acetic acid;
DOI:10.1248/cpb.39.2855
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 70 percent / H2, 70percent aq. HClO4 / 10percent Pd/C / acetic acid / 760 Torr / 1.) 40 deg C, 4 h, 2.) 60 deg C, 13 h
2: 1.) K2CO3 / 1.) DMF, 88 deg C, 1 h, 2.) room temperature, 3 h
3: 81 percent / 2 N aq. H2SO4 / acetic acid / 1 h / Heating
With
perchloric acid; sulfuric acid; hydrogen; potassium carbonate;
palladium on activated charcoal;
In
acetic acid;
DOI:10.1248/cpb.39.2855