Technology Process of C22H22F5NO2
There total 5 articles about C22H22F5NO2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: dichloromethane / 0 °C
2: potassium carbonate / dimethyl sulfoxide / 0.25 h / 140 °C / Microwave irradiation
With
potassium carbonate;
In
dichloromethane; dimethyl sulfoxide;
DOI:10.1016/j.bmcl.2011.09.018
- Guidance literature:
-
Multi-step reaction with 4 steps
1: copper(l) iodide; dichlorobis(tri-O-tolylphosphine)palladium; triethylamine / acetonitrile / 20 °C
2: iron; acetic acid / 0.5 h / 60 °C
3: dichloromethane / 0 °C
4: potassium carbonate / dimethyl sulfoxide / 0.25 h / 140 °C / Microwave irradiation
With
copper(l) iodide; dichlorobis(tri-O-tolylphosphine)palladium; iron; potassium carbonate; acetic acid; triethylamine;
In
dichloromethane; dimethyl sulfoxide; acetonitrile;
1: Sonogashira coupling;
DOI:10.1016/j.bmcl.2011.09.018
- Guidance literature:
-
Multi-step reaction with 3 steps
1: iron; acetic acid / 0.5 h / 60 °C
2: dichloromethane / 0 °C
3: potassium carbonate / dimethyl sulfoxide / 0.25 h / 140 °C / Microwave irradiation
With
iron; potassium carbonate; acetic acid;
In
dichloromethane; dimethyl sulfoxide;
DOI:10.1016/j.bmcl.2011.09.018