tetrahydro-2-furancarboximidamide hydrochloride

Base Information

• Chemical Name: tetrahydro-2-furancarboximidamide hydrochloride
• CAS No.: 619329-27-0
• Molecular Formula: C₅H₁₀N₂O*ClH
• Molecular Weight: 150.608
• Mol file: 619329-27-0.mol

Synonyms:

Chemical Property of tetrahydro-2-furancarboximidamide hydrochloride

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tetrahydro-2-furancarboximidamide hydrochloride

There total 5 articles about tetrahydro-2-furancarboximidamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

methyl tetrahydrofuran-2-carboxylate (37443-42-8) → tetrahydro-2-furancarboximidamide hydrochloride (619329-27-0)

Guidance literature:

With trimethylaluminum; ammonium chloride; In hexane; toluene; at 0 - 80 ℃;

Reference yield:

tetrahydro-2-furancarboxylic acid (16874-33-2) → tetrahydro-2-furancarboximidamide hydrochloride (619329-27-0)

Guidance literature:

Multi-step reaction with 3 steps

1: ammonia; 1,1'-carbonyldiimidazole / N,N-dimethyl-formamide

2: dichloromethane

3: ammonium chloride / methanol

With dichloromethane; ammonia; ammonium chloride; 1,1'-carbonyldiimidazole; In methanol; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2011.03.038

Reference yield:

C6H11NO2*ClH → tetrahydro-2-furancarboximidamide hydrochloride (619329-27-0)

Guidance literature:

With ammonium chloride; In methanol;

DOI:10.1016/j.bmcl.2011.03.038

upstream raw materials:

methyl tetrahydrofuran-2-carboxylate

tetrahydro-2-furancarboxylic acid

tetrahydrofuran-2-carboxamide

Refernces

• 1、 -. "PROPANE-1,3-DION DERIVATIVE OR SALT THEREOF". Page/Page column 31. . Retrieved 2008/06/13.