Thienpydin

Base Information

• Chemical Name: Thienpydin
• CAS No.: 26155-11-3
• Molecular Formula: Br*C₁₁H₁₀NS
• Molecular Weight: 268.177
• NSC Number: 405305
• UNII: 6M97GRF5BA
• Mol file: 26155-11-3.mol

Synonyms:1-(2-(2-thienyl)vinyl)pyridinium bromide;thienpydin;thienpydin bromide, (E)-isomer

Chemical Property of Thienpydin

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 266.97173
• Heavy Atom Count: 14
• Complexity: 173

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=[N+](C=C1)C=CC2=CC=CS2.[Br-]
• Isomeric SMILES: C1=CC=[N+](C=C1)/C=C/C2=CC=CS2.[Br-]

Technology Process of Thienpydin

There total 5 articles about Thienpydin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (E)-1-<2-(2-thienyl)vinyl>pyridinium bromide (26155-11-3)

Guidance literature:

With benzoyl chloride; at 200 ℃;

DOI:10.1021/ja01162a045

Reference yield:

1-(2-hydroxy-2-thienylethyl)pyridinium bromide (26031-81-2) → (E)-1-<2-(2-thienyl)vinyl>pyridinium bromide (26155-11-3)

Guidance literature:

With benzoyl chloride; at 190 - 200 ℃;

DOI:10.1002/jhet.5570330111

Reference yield:

pyridine (110-86-1) → (E)-1-<2-(2-thienyl)vinyl>pyridinium bromide (26155-11-3)

Guidance literature:

Multi-step reaction with 3 steps

1: benzene / 4 h / Heating

2: NaBH₄ / H₂O / Ambient temperature

3: benzoyl chloride / 190 - 200 °C

With sodium tetrahydroborate; benzoyl chloride; In water; benzene;

DOI:10.1002/jhet.5570330111

upstream raw materials:

1-(2-hydroxy-2-thienylethyl)pyridinium bromide

pyridine

2-Bromoacetylthiophene

2-(1-pyeidinium)-1-(2-thienyl)ethanone bromide

Refernces