Technology Process of Propanoic acid, 2-(4-methylphenoxy)-, (2R)-
There total 12 articles about Propanoic acid, 2-(4-methylphenoxy)-, (2R)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
p-cresol; R-(+)-2-bromopropionic acid;
With
sodium hydride;
In
tetrahydrofuran; mineral oil;
at 20 ℃;
for 5h;
With
sodium hydroxide;
In
tetrahydrofuran; mineral oil;
at 20 ℃;
for 1h;
With
hydrogenchloride;
In
tetrahydrofuran; water; mineral oil;
pH=1;
- Guidance literature:
-
With
Nocardia diaphanozonaria cells; glycerol; peptone;
beef extract; yeast extract;
In
water;
at 30 ℃;
for 48h;
pH=7.0;
Title compound not separated from byproducts;
DOI:10.1021/jo034253x
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 26 percent / sodium hydride / tetrahydrofuran / 14 h / 20 °C
2: 94 percent / potassium hydroxide / ethanol; H2O / 4 h / 0 °C
3: Nocardia diaphanozonaria cells; glycerol; peptone / beef extract; yeast extract / H2O / 48 h / 30 °C / pH 7.0
With
potassium hydroxide; Nocardia diaphanozonaria cells; sodium hydride; glycerol; peptone;
beef extract; yeast extract;
In
tetrahydrofuran; ethanol; water;
DOI:10.1021/jo034253x
