5-ethyl-3-methoxybenzene-1,2-diol

Base Information

• Chemical Name: 5-ethyl-3-methoxybenzene-1,2-diol
• CAS No.: 7452-04-2
• Molecular Formula: C₉H₁₂O₃
• Molecular Weight: 168.192
• Mol file: 7452-04-2.mol

Synonyms:

Chemical Property of 5-ethyl-3-methoxybenzene-1,2-diol

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-ethyl-3-methoxybenzene-1,2-diol

There total 8 articles about 5-ethyl-3-methoxybenzene-1,2-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 3-(4-(5-ethyl-2-hydroxy-3-methoxyphenoxy)-3-methoxyphenyl)propanoate → 4-ethylcatechol (1124-39-6) + 4-Ethylguaiacol (2785-89-9) + 5-ethylbenzene-1,2,3-triol (66125-16-4) + 3-(3-methoxyphenyl)propanoic acid ethyl ester (7116-39-4) + ethyl 3-(4-hydroxy-3-methoxyphenyl)propanoate (61292-90-8) + 3-(3-hydroxy-phenyl)propionic acid ethyl ester (34708-60-6) + 5-ethyl-3-methoxybenzene-1,2-diol (7452-04-2) + Ethyl dihydrocaffeate (3967-57-5)

Guidance literature:

ethyl 3-(4-(5-ethyl-2-hydroxy-3-methoxyphenoxy)-3-methoxyphenyl)propanoate; With platinum-nickel nanoclusters on activated carbon; hydrogen; potassium hexamethylsilazane; In m-xylene; at 180 ℃; for 18h; under 775.743 Torr;

With N,O-Bis(trimethylsilyl)trifluoroacetamide; In m-xylene; at 65 ℃; for 1h; Overall yield = 41 %;

DOI:10.1002/anie.201509133

Reference yield:

2-(benzyloxy)-5-ethyl-1-methoxy-3-(2-methoxy-4-propylphenoxy)benzene → 3-n-propylphenol (621-27-2) + 4-ethylcatechol (1124-39-6) + 4-Ethylguaiacol (2785-89-9) + 2-methoxy-4-propylphenol (58539-27-8) + 5-ethylbenzene-1,2,3-triol (66125-16-4) + 4-propylbenzene-1,2-diol (2525-02-2) + 3-propylanisole (62103-69-9) + 5-ethyl-3-methoxybenzene-1,2-diol (7452-04-2)

Guidance literature:

2-(benzyloxy)-5-ethyl-1-methoxy-3-(2-methoxy-4-propylphenoxy)benzene; With platinum-nickel nanoclusters on activated carbon; hydrogen; potassium hexamethylsilazane; In m-xylene; at 180 ℃; for 24h; under 775.743 Torr;

With N,O-Bis(trimethylsilyl)trifluoroacetamide; In m-xylene; at 65 ℃; for 1h; Overall yield = 85 %;

DOI:10.1002/anie.201509133

Reference yield:

4-ethyl-2-methoxy-6-(2-methoxy-4-propylphenoxy)phenol → 3-n-propylphenol (621-27-2) + 4-ethylcatechol (1124-39-6) + 4-Ethylguaiacol (2785-89-9) + 2-methoxy-4-propylphenol (58539-27-8) + 5-ethylbenzene-1,2,3-triol (66125-16-4) + 4-propylbenzene-1,2-diol (2525-02-2) + 3-propylanisole (62103-69-9) + 5-ethyl-3-methoxybenzene-1,2-diol (7452-04-2)

Guidance literature:

4-ethyl-2-methoxy-6-(2-methoxy-4-propylphenoxy)phenol; With platinum-nickel nanoclusters on activated carbon; hydrogen; potassium hexamethylsilazane; In m-xylene; at 180 ℃; for 24h; under 775.743 Torr;

With N,O-Bis(trimethylsilyl)trifluoroacetamide; In m-xylene; at 65 ℃; for 1h; Overall yield = 78 %;

DOI:10.1002/anie.201509133

Refernces