o-cyanophenylacetyl chloride

Base Information

• Chemical Name: o-cyanophenylacetyl chloride
• CAS No.: 55086-26-5
• Molecular Formula: C₉H₆ClNO
• Molecular Weight: 179.606
• Mol file: 55086-26-5.mol

Synonyms:

Chemical Property of o-cyanophenylacetyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of o-cyanophenylacetyl chloride

There total 2 articles about o-cyanophenylacetyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(2-aminophenyl)acetic acid (3342-78-7) → o-cyanophenylacetyl chloride (55086-26-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) NaNO₂, 2.) CuSO₄

2: SOCl₂

With thionyl chloride; copper(II) sulfate; sodium nitrite;

DOI:10.1002/ardp.19883210506

Reference yield:

→ o-cyanophenylacetyl chloride (55086-26-5)

Guidance literature:

(2-Cyanphenyl)-essigsaeure, Phosphorpentachlorid;

Reference yield:

o-cyanophenylacetyl chloride (55086-26-5) + toluene (108-88-3,15644-74-3,16713-13-6) → 2-(2-oxo-2-(p-tolyl)ethyl)benzonitrile (67237-71-2)

Guidance literature:

Friedel-Crafts conditions;

upstream raw materials:

2-(2-aminophenyl)acetic acid

Downstream raw materials:

2-(2-cyanophenyl)acetamide

2-(2-oxo-2-(p-tolyl)ethyl)benzonitrile

1-(2-Cyanophenyl)-1-phenyl-1-ethanone

Refernces